Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.64 |
| ▸ | BRAF | P15056 | 2/20 | 0.64 |
| ▸ | RET | P07949 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | ATM | Q13315 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | KIT | P10721 | 1/20 | 0.57 |
| ▸ | HCK | P08631 | 1/20 | 0.56 |
| ▸ | NR2C2 | P49116 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | UBE2N | P61088 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.54 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.54 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.54 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.54 |
| ▸ | MAP3K20 | Q9NYL2 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26215628 | 0.88 | HTT (0.58) | RETMAPTKMT2AATMHTT | |
| SCHEMBL26215023 | 0.87 | EGFR (0.64) | EGFRBRAFRETMAPTKMT2A | |
| SCHEMBL26215982 | 0.86 | MAPT (0.52) | EGFRBRAFMAPTKMT2AATM | |
| SCHEMBL26215332 | 0.84 | ATM (0.59) | EGFRBRAFRETMAPTKMT2A | |
| SCHEMBL1420251 | 0.82 | EPHA2 (0.62) | EGFRBRAFRETMAPTKMT2A | |
| SCHEMBL26214307 | 0.81 | EPHA2 (0.84) | RETMAPTKMT2AATMMAPK1 | |
| SCHEMBL20568434 | 0.81 | HTT (0.62) | EGFRBRAFMAPTATMHTT | |
| SCHEMBL28054362 | 0.78 | HTT (0.65) | BRAFMAPTKMT2AATMHTT | |
| SCHEMBL17181924 | 0.78 | EPHA2 (0.66) | EGFRBRAFRETMAPTKMT2A | |
| SCHEMBL20568437 | 0.78 | EPHA2 (0.61) | BRAFRETMAPTATMHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023168107-A2 | COMPOUNDS AND COMPOSITIONS FOR ANITMALARIAL THERAPEUTIC AND PROPHYLACTIC USE | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) | 2023-09-07 | — | — | WO | disclosed |