Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.58 |
| ▸ | ATM | Q13315 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | HCK | P08631 | 1/20 | 0.57 |
| ▸ | NR2C2 | P49116 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | CLK1 | P49759 | 1/20 | 0.55 |
| ▸ | KIT | P10721 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | RET | P07949 | 1/20 | 0.53 |
| ▸ | KDR | P35968 | 1/20 | 0.53 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.53 |
| ▸ | MAP3K7 | O43318 | 3/20 | 0.53 |
| ▸ | MAP4K2 | Q12851 | 3/20 | 0.53 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MAP3K20 | Q9NYL2 | 1/20 | 0.53 |
| ▸ | FES | P07332 | 1/20 | 0.53 |
| ▸ | FER | P16591 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26215337 | 0.88 | EGFR (0.64) | HTTATMMAPK1HCKNR2C2 | |
| SCHEMBL1420251 | 0.87 | EPHA2 (0.62) | HTTATMMAPK1MAPTCLK1 | |
| SCHEMBL20568434 | 0.85 | HTT (0.62) | HTTATMMAPK1HCKNR2C2 | |
| SCHEMBL26215332 | 0.83 | ATM (0.59) | HTTATMMAPTCLK1KIT | |
| SCHEMBL26215023 | 0.83 | EGFR (0.64) | ATMMAPTKITKMT2ARET | |
| SCHEMBL28054362 | 0.82 | HTT (0.65) | HTTATMMAPK1HCKNR2C2 | |
| SCHEMBL20568437 | 0.82 | EPHA2 (0.61) | HTTATMMAPK1HCKNR2C2 | |
| SCHEMBL3389535 | 0.82 | HTT (0.71) | HTTATMMAPK1HCKNR2C2 | |
| SCHEMBL15690013 | 0.81 | MAPT (0.58) | HTTATMMAPK1HCKNR2C2 | |
| SCHEMBL16380144 | 0.81 | RET (0.63) | HTTATMMAPK1HCKNR2C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023168107-A2 | COMPOUNDS AND COMPOSITIONS FOR ANITMALARIAL THERAPEUTIC AND PROPHYLACTIC USE | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) | 2023-09-07 | — | — | WO | disclosed |