⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20669010 | 0.71 | — | — | |
| SCHEMBL24564520 | 0.68 | — | — | |
| SCHEMBL12646554 | 0.65 | ALDH1A1 (0.41) | — | |
| SCHEMBL22083910 | 0.65 | ALDH1A1 (0.41) | — | |
| SCHEMBL24564521 | 0.64 | — | — | |
| SCHEMBL21675666 | 0.64 | HMGCR (0.34) | — | |
| SCHEMBL21651170 | 0.64 | — | — | |
| SCHEMBL18469074 | 0.62 | — | — | |
| SCHEMBL19455056 | 0.61 | — | — | |
| SCHEMBL23732288 | 0.61 | NOS2 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230286904-A1 | INHIBITORS OF YAP/TAZ-TEAD ONCOPROTEINS, SYNTHESIS AND USE THEREOF | BRIDGENE BIOSCIENCES, INC. | 2023-09-14 | — | — | US | disclosed |