SCHEMBL26219495

SCHEMBL26219495

Cc1cccc2c3ccccc3n(Cc3cccc4ccccc34)c12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 2/20 0.50
▸ KDM4A O75164 1/20 0.50
▸ HSD17B10 Q99714 1/20 0.50
▸ ALKBH5 Q6P6C2 1/20 0.50
▸ FTO Q9C0B1 1/20 0.50
▸ DNM1 Q05193 1/20 0.46
▸ CMA1 P23946 1/20 0.45
▸ KDM4E B2RXH2 1/20 0.45
▸ ALDH1A1 P00352 2/20 0.44
▸ TP53 P04637 1/20 0.44
▸ HPGD P15428 1/20 0.44
▸ TSHR P16473 1/20 0.44
▸ KMT2A Q03164 1/20 0.44
▸ NPC1 O15118 1/20 0.43
▸ GALR3 O60755 1/20 0.43
▸ NR2F2 P24468 1/20 0.43
▸ RAB9A P51151 1/20 0.43
▸ CHRNE Q04844 1/20 0.43
▸ CYP2A6 P11509 1/20 0.43
▸ ACHE P22303 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8178240 0.77 ALKBH5 (0.59) LMNAHSD17B10ALKBH5FTOKDM4E
SCHEMBL29093444 0.77 CHRNE (0.63) LMNAKDM4AHSD17B10DNM1KDM4E
SCHEMBL30616063 0.77 CHRNE (0.63) LMNAKDM4AHSD17B10DNM1KDM4E
SCHEMBL18406152 0.75 CHRNE (0.42) LMNAKDM4AHSD17B10DNM1CMA1
SCHEMBL20363636 0.74 ALKBH5 (0.61) LMNAALKBH5FTOKDM4EALDH1A1
SCHEMBL3277134 0.74 F10 (0.57) CMA1KDM4EMCL1BAD
SCHEMBL14492832 0.74 CYP19A1 (0.59) LMNAHSD17B10DNM1CMA1KDM4E
SCHEMBL15682202 0.73 ALKBH5 (0.54) LMNAHSD17B10ALKBH5FTODNM1
SCHEMBL2156667 0.72 F10 (0.47) LMNAHSD17B10DNM1CMA1KDM4E
SCHEMBL3276218 0.72 FDPS (0.56) CMA1KMT2AMCL1BAD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240023435-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-01-18 — — US disclosed
US-20230399350-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-12-14 — — US disclosed
US-20230292586-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-14 — — US disclosed
US-20230292606-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-14 — — US disclosed
US-20230292592-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-14 — — US disclosed
US-20230279029-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230399350-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, OSBP LMNA 3405/4885KDM4A 3972/4885HSD17B10 475/4885
US-20230292592-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, OSBP LMNA 3405/4885KDM4A 3972/4885HSD17B10 475/4885
US-20230279029-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, EHD1 LMNA 1657/4885KDM4A 3745/4885HSD17B10 533/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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