Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | SERPINA3 | P01011 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NAMPT | P43490 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20974841 | 0.93 | SERPINA3 (0.44) | LMNASERPINA3TSHRNAMPTCA1 | |
| SCHEMBL19575754 | 0.92 | HDAC1 (0.39) | SERPINA3MEN1KMT2ANAMPTCA1 | |
| SCHEMBL20972809 | 0.92 | LMNA (0.42) | LMNATSHRNPSR1MEN1KMT2A | |
| SCHEMBL20975174 | 0.91 | NAMPT (0.42) | SERPINA3NAMPTCA1CA2CA4 | |
| SCHEMBL20975301 | 0.91 | LMNA (0.42) | LMNATSHRNPSR1MEN1KMT2A | |
| SCHEMBL20972933 | 0.90 | LMNA (0.42) | LMNATSHRNPSR1MEN1KMT2A | |
| SCHEMBL20975131 | 0.90 | ALDH1A1 (0.40) | LMNATSHRNPSR1MEN1KMT2A | |
| SCHEMBL20975399 | 0.89 | LMNA (0.43) | LMNATSHRNPSR1MEN1KMT2A | |
| SCHEMBL20974411 | 0.89 | CTSL (0.39) | LMNATSHRNPSR1MEN1KMT2A | |
| SCHEMBL20974372 | 0.89 | LMNA (0.41) | LMNATSHRNPSR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3452477-B1 | ADENINE DERIVATIVES AS PROTEIN KINASE INHIBITORS | B C I PHARMA (BE) | 2023-09-13 | — | — | EP | disclosed |