Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 4/20 | 0.39 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.36 |
| ▸ | NAMPT | P43490 | 11/20 | 0.34 |
| ▸ | WNT3A | P56704 | 2/20 | 0.33 |
| ▸ | ATR | Q13535 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17998818 | 0.87 | BTK (0.42) | BTKSOS1ATR | |
| SCHEMBL14914480 | 0.82 | BTK (0.54) | BTK | |
| SCHEMBL29741962 | 0.82 | BTK (0.54) | BTK | |
| SCHEMBL26222770 | 0.77 | WNT3A (0.51) | NAMPTWNT3A | |
| SCHEMBL26222768 | 0.77 | WNT3A (0.41) | WNT3A | |
| SCHEMBL2587306 | 0.75 | ACVR1 (0.38) | BTKATR | |
| SCHEMBL28380327 | 0.71 | BTK (0.52) | BTK | |
| SCHEMBL29742101 | 0.70 | BTK (0.49) | BTK | |
| SCHEMBL14926113 | 0.70 | BTK (0.49) | BTK | |
| SCHEMBL24374839 | 0.70 | BTK (0.49) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230279012-A1 | HETEROARYL PYRIDONE AND AZA-PYRIDONE COMPOUNDS | GENENTECH, INC. (US) | 2023-09-07 | — | — | US | disclosed |
| US-20230279012-A1 | HETEROARYL PYRIDONE AND AZA-PYRIDONE COMPOUNDS | GENENTECH, INC. (US) | 2023-09-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230279012-A1 | HETEROARYL PYRIDONE AND AZA-PYRIDONE COMPOUNDS | PDXK, BTK, TYK2 | BTK 2/4885SOS1 2499/4885NAMPT 897/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.