Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL242270 | 0.86 | L3MBTL1 (0.41) | KMT2AALDH1A1L3MBTL1KDM4ELMNA | |
| SCHEMBL10136052 | 0.81 | NPFFR1 (0.39) | KMT2AALDH1A1L3MBTL1KDM4ELMNA | |
| SCHEMBL10046524 | 0.81 | NPFFR1 (0.39) | KMT2AALDH1A1L3MBTL1KDM4ELMNA | |
| SCHEMBL11632667 | 0.80 | L3MBTL1 (0.38) | PCSK9KMT2AALDH1A1L3MBTL1KDM4E | |
| SCHEMBL11632674 | 0.80 | L3MBTL1 (0.38) | PCSK9KMT2AALDH1A1L3MBTL1KDM4E | |
| SCHEMBL20276637 | 0.78 | KMT2A (0.39) | PCSK9KMT2AALDH1A1L3MBTL1KDM4E | |
| SCHEMBL6798906 | 0.77 | L3MBTL1 (0.38) | PCSK9KMT2AALDH1A1L3MBTL1KDM4E | |
| SCHEMBL5257223 | 0.77 | L3MBTL1 (0.38) | PCSK9KMT2AALDH1A1L3MBTL1KDM4E | |
| SCHEMBL4815986 | 0.77 | — | — | |
| SCHEMBL2734924 | 0.77 | APLNR (0.36) | KMT2AALDH1A1L3MBTL1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023170240-A1 | ANTI-CEACAM5 ANTIBODIES AND CONJUGATES AND USES THEREOF | MERCK PATENT GMBH (DE) | 2023-09-14 | — | — | WO | disclosed |