Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.37 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5257223 | 1.00 | L3MBTL1 (0.38) | L3MBTL1SYKSERPINE1PCSK9KMT2A | |
| SCHEMBL20276637 | 0.88 | KMT2A (0.39) | L3MBTL1SYKSERPINE1PCSK9KMT2A | |
| SCHEMBL11632674 | 0.86 | L3MBTL1 (0.38) | L3MBTL1SYKSERPINE1PCSK9KMT2A | |
| SCHEMBL11632667 | 0.86 | L3MBTL1 (0.38) | L3MBTL1SYKSERPINE1PCSK9KMT2A | |
| SCHEMBL880771 | 0.84 | KMT2A (0.37) | L3MBTL1SYKSERPINE1PCSK9KMT2A | |
| SCHEMBL18226807 | 0.84 | CTSS (0.40) | L3MBTL1SYKSERPINE1KMT2AALDH1A1 | |
| SCHEMBL18226806 | 0.84 | CTSS (0.40) | L3MBTL1SYKSERPINE1KMT2AALDH1A1 | |
| SCHEMBL18221182 | 0.84 | MEN1 (0.46) | KMT2AMEN1GAATDP1CA1 | |
| SCHEMBL17227817 | 0.84 | MEN1 (0.46) | KMT2AMEN1GAATDP1CA1 | |
| SCHEMBL29583631 | 0.82 | L3MBTL1 (0.36) | L3MBTL1SYKSERPINE1PCSK9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6747021-B2 | ANTICARCINOGENIC AGENT WITH LOW TOXICITY | ELI LILLY AND COMPANY | 2004-06-08 | — | — | US | disclosed |
| US-20020065261-A1 | Anticarcinogenic agent with low toxicity | UNIVERSITY OF HAWAII | 2002-05-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020065261-A1 | Anticarcinogenic agent with low toxicity | HCCS, TP53, GSTA1 | L3MBTL1 1203/4885SYK 4757/4885SERPINE1 3856/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.