⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24637992 | 0.79 | HSD11B1 (0.34) | — | |
| SCHEMBL22794823 | 0.74 | PIK3CD (0.47) | — | |
| SCHEMBL23946046 | 0.73 | GBA1 (0.33) | — | |
| SCHEMBL4546629 | 0.72 | PIK3CD (0.31) | — | |
| SCHEMBL24571869 | 0.70 | — | — | |
| SCHEMBL23945854 | 0.69 | ALDH1A1 (0.33) | — | |
| SCHEMBL24637871 | 0.68 | GBA1 (0.38) | — | |
| SCHEMBL21456345 | 0.68 | KDM1A (0.33) | — | |
| SCHEMBL23945856 | 0.67 | PIK3CD (0.38) | — | |
| SCHEMBL23695847 | 0.67 | PIK3CD (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11746120-B2 | Stat degraders and uses thereof | KYMERA THERAPEUTICS, INC. (US) | 2023-09-05 | — | — | US | disclosed |