Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24637992 | 0.87 | HSD11B1 (0.34) | LMNA | |
| SCHEMBL25826926 | 0.79 | SLC18A3 (0.36) | GBA1LMNASLC18A3 | |
| SCHEMBL26472996 | 0.78 | PIK3CD (0.38) | LMNA | |
| SCHEMBL25702363 | 0.78 | PIK3CD (0.38) | LMNA | |
| SCHEMBL24637968 | 0.78 | SLC6A3 (0.39) | GBA1LMNA | |
| SCHEMBL24638030 | 0.77 | OPRM1 (0.41) | LMNA | |
| SCHEMBL26173940 | 0.77 | SLC6A3 (0.33) | — | |
| SCHEMBL23556463 | 0.73 | ALDH1A1 (0.38) | — | |
| SCHEMBL22856348 | 0.72 | GBA1 (0.37) | GBA1LMNA | |
| SCHEMBL8373561 | 0.71 | OPRM1 (0.34) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192598-A1 | HETEROCYCLES AND USES THEREOF | KUMQUAT BIOSCIENCES INC. (US) | 2022-09-15 | — | — | WO | disclosed |