SCHEMBL262291

SCHEMBL262291

C=CCNC(=O)OC(C)(C)C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.47
KMT2A Q03164 2/20 0.44
MEN1 O00255 1/20 0.44
GAA P10253 1/20 0.44
TSHR P16473 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
MAPT P10636 1/20 0.42
MAOA P21397 1/20 0.41
MAOB P27338 1/20 0.41
CA1 P00915 4/20 0.40
CA12 O43570 3/20 0.40
CA7 P43166 2/20 0.40
CA14 Q9ULX7 1/20 0.40
CA2 P00918 3/20 0.39
CA9 Q16790 2/20 0.39
EPHX1 P07099 1/20 0.39
FAAH O00519 1/20 0.39
PKM P14618 1/20 0.39
PTPN11 Q06124 1/20 0.38
CTSK P43235 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glycine SCHEMBL6684282 0.89 KMT2A (0.41) TDP1KMT2AMEN1GAATSHR
SCHEMBL24503819 0.86 TDP1 (0.40) TDP1KMT2AMEN1GAATSHR
SCHEMBL9300578 0.84 TSHR (0.39) TDP1KMT2AMEN1GAATSHR
SCHEMBL4893443 0.83 TDP1 (0.49) TDP1KMT2AMEN1GAASMN1; SMN2
SCHEMBL8775013 0.83 TDP1 (0.47) TDP1KMT2AMEN1GAAMAOA
SCHEMBL2404127 0.83 TDP1 (0.50) TDP1KMT2AMEN1GAAMAOA
SCHEMBL18262007 0.83 TDP1 (0.50) TDP1KMT2AMEN1GAAMAOA
SCHEMBL18262010 0.83 TDP1 (0.50) TDP1KMT2AMEN1GAAMAOA
SCHEMBL18487257 0.83 TDP1 (0.50) TDP1KMT2AMEN1GAAMAOA
SCHEMBL8083217 0.81 TDP1 (0.42) TDP1KMT2AMEN1GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 756 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025007765-A1 NOISE REDUCTION COMPOSITE COTTON MATERIAL FOR AIRCRAFT CABIN, PREPARATION METHOD THEREFOR AND USE THEREOF 峰特(浙江)新材料有限公司 2025-01-09 WO claimed
WO-2025002037-A1 THERMAL INSULATION MATERIAL FOR AIRCRAFT CABIN INTERLAYER, AND PREPARATION METHOD THEREFOR 峰特(浙江)新材料有限公司 2025-01-02 WO claimed
CN-118515445-A Nano-coated modified silicon graphene material and preparation method thereof 浙江尧欣塑胶有限公司 2024-08-20 CN claimed
CN-118206836-A Chlorinated polyvinyl chloride material for aging resistance and fire resistance of wooden door 浙江嘉信门业有限公司 2024-06-18 CN claimed
CN-118063328-A Efficient low-cost preparation method of 2, 3-dibromo-1-propylamine salt 南宁师范大学 2024-05-24 CN claimed
CN-117126349-A Flexible silencing material for aircraft air distribution system 郑州峰泰纳米材料有限公司 2023-11-28 CN claimed
CN-116731420-A Heat insulation material for aircraft cabin interlayer and preparation method thereof 郑州峰泰纳米材料有限公司 2023-09-12 CN claimed
CN-116731421-A Noise-reduction composite cotton material for aircraft passenger cabin and preparation method and application thereof 郑州峰泰纳米材料有限公司 2023-09-12 CN claimed
EP-3472174-B1 METHOD FOR THE PREPARATION OF SUBSTITUTED THIOLACTONES, NEW SUBSTITUTED THIOLACTONES, AND USES THEREOF CENTRE NAT RECH SCIENT (FR) 2020-11-18 EP claimed
US-20190202849-A1 METHOD FOR THE PREPARATION OF SUBSTITUTED THIOLACTONES, NEW SUBSTITUTED THIOLACTONES AND USES THEREOF CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2019-07-04 US claimed
WO-2010056506-A1 DIACYLGLYCEROL ACLYTRANSFERASE INHIBITORS VIA PHARMACEUTICALS, INC. (US) 2010-05-20 WO claimed
US-7393847-B2 Imidazopyridazinediones, their preparation and their use as pharmaceutical compositions BOEHRINGER INGLEHEIM INTERNATIONAL GMBH (DE) 2008-07-01 US claimed
EP-1368349-B1 XANTHINE DERIVATIVE, PRODUCTION AND USE THEREOF AS A MEDICAMENT BOEHRINGER INGELHEIM PHARMA (DE) 2007-02-14 EP claimed
US-6495243-B1 Recording substrates for ink jet printing XEROX CORPORATION 2002-12-17 US claimed
US-6319310-B1 FOR ACOUSTIC INK JET PRINTING; TRANSPARENCY, GLOSS, CREASE RESISTANCE XEROX CORPORATION 2001-11-20 US claimed
US-6110265-A Ink compositions XEROX CORPORATION (US) 2000-08-29 US claimed
US-6106601-A MIXTURE CONTAINING OXAZOLINE AND THIOUREA COMPOUNDS XEROX CORPORATION (US) 2000-08-22 US claimed
US-6045607-A FIRST AND SECOND SOLID CARBAMATES WITH A DISSIMILAR MELTING POINTS; LIGHTFASTNESS COMPONENT; A LIGHTFASTNESS ANTIOXIDANTS, AND A COLORANT; USEFUL FOR ACOUSTIC INK PRINTING XEROX CORPORATION (US) 2000-04-04 US claimed
US-5759734-A Method of generating simulated photographic-quality images on luminescent melt-formed backing substrates XEROX CORPORATION (US) 1998-06-02 US claimed
EP-0454121-B1 Azatetracyclic compounds SEARLE & CO (US) 1996-11-13 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190202849-A1 METHOD FOR THE PREPARATION OF SUBSTITUTED THIOLACTONES, NEW SUBSTITUTED THIOLACTONES AND USES THEREOF TST, ALG1, TMT1A TDP1 2656/4885KMT2A 3885/4885MEN1 1802/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.