Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.45 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.45 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.44 |
| ▸ | ATR | Q13535 | 1/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | CTSE | P14091 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21410624 | 1.00 | GPR119 (0.47) | GPR119NR3C1DDB1CRBNPIK3CA | |
| SCHEMBL22875531 | 0.80 | GPR119 (0.44) | GPR119NR3C1DDB1CRBNPIK3CA | |
| SCHEMBL28479016 | 0.78 | GPR119 (0.48) | GPR119NR3C1DDB1CRBNPIK3CA | |
| SCHEMBL22875532 | 0.77 | GPR119 (0.47) | GPR119NR3C1DDB1CRBNPIK3CA | |
| SCHEMBL17610366 | 0.76 | GPR119 (0.50) | GPR119NR3C1DDB1CRBNPIK3CA | |
| SCHEMBL19450209 | 0.76 | ALOX15 (0.57) | GPR119NR3C1DDB1CRBNPIK3CA | |
| SCHEMBL17610518 | 0.76 | GPR119 (0.48) | GPR119NR3C1DDB1CRBNPIK3CA | |
| SCHEMBL23393506 | 0.75 | NR3C1 (0.52) | GPR119NR3C1DDB1CRBNPIK3CA | |
| SCHEMBL2386226 | 0.75 | GPR119 (0.51) | GPR119NR3C1DDB1CRBNPIK3CA | |
| SCHEMBL7882891 | 0.74 | NR3C1 (0.48) | GPR119NR3C1DDB1CRBNPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111902141-A | Glucocerebroside binders for IKAROS degradation | C4医药公司 | 2020-11-06 | — | — | CN | disclosed |