SCHEMBL2623451

SCHEMBL2623451

COc1ccc(Oc2cccc(-c3ccc(N(c4ccc(-c5cccc(Oc6ccc(C=O)cc6)c5)cc4)c4ccc(-c5cccc(Oc6ccc(C=O)cc6)c5)cc4)cc3)c2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD1 P21728 1/20 0.49
ALDH1A1 P00352 1/20 0.49
CYP2A6 P11509 1/20 0.49
ABL1 P00519 1/20 0.47
ABCB1 P08183 1/20 0.47
BCR P11274 1/20 0.47
LMNA P02545 1/20 0.45
HPGD P15428 1/20 0.45
TSHR P16473 1/20 0.45
FFAR1 O14842 2/20 0.44
FFAR4 Q5NUL3 2/20 0.44
HDAC4 P56524 1/20 0.42
HDAC2 Q92769 1/20 0.42
HDAC8 Q9BY41 1/20 0.42
PGR P06401 1/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
TTR P02766 1/20 0.41
ERN1 O75460 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2632213 0.93 DRD1 (0.55) DRD1ALDH1A1CYP2A6LMNAFFAR1
SCHEMBL3804053 0.92 ALDH1A1 (0.58) DRD1ALDH1A1CYP2A6ABL1ABCB1
SCHEMBL10028278 0.85 ALDH1A1 (0.68) ALDH1A1CYP2A6LMNATSHRPGR
SCHEMBL17199711 0.85 ALDH1A1 (0.68) DRD1ALDH1A1CYP2A6LMNATSHR
SCHEMBL2623457 0.84 DRD1 (0.45) DRD1ALDH1A1LMNAFFAR1FFAR4
SCHEMBL19275027 0.82 ALDH1A1 (0.59) DRD1ALDH1A1CYP2A6LMNAHPGD
SCHEMBL14452808 0.82 ALDH1A1 (0.59) DRD1ALDH1A1CYP2A6LMNAHPGD
SCHEMBL2581063 0.82 DRD1 (0.64) DRD1ALDH1A1CYP2A6ABL1ABCB1
SCHEMBL13385299 0.81 ALDH1A1 (0.58) ALDH1A1CYP2A6NPC1RAB9ATDP1
SCHEMBL23918546 0.81 ALDH1A1 (0.61) ALDH1A1CYP2A6ABL1ABCB1BCR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150079714-A1 COMPOSITION FOR USE IN ORGANIC DEVICE, POLYMER FILM, AND ORGANIC ELECTROLUMINESCENT ELEMENT MITSUBISHI CHEMICAL CORPORATION (JP) 2015-03-19 US disclosed
US-20120091443-A1 COMPOSITION FOR USE IN ORGANIC DEVICE, POLYMER FILM, AND ORGANIC ELECTROLUMINESCENT ELEMENT MITSUBISHI CHEMICAL CORPORATION (JP) 2012-04-19 US disclosed