SCHEMBL23918546

SCHEMBL23918546

COc1ccc(N(c2ccc(C=O)cc2)c2ccc(/C=C/c3ccc(-c4ccc(/C=C/c5ccc(N(c6ccc(OC)cc6)c6ccc(OC)cc6)cc5)cc4)cc3)cc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.61
CYP2A6 P11509 1/20 0.61
HDAC8 Q9BY41 2/20 0.49
HDAC6 Q9UBN7 2/20 0.49
HDAC3 O15379 1/20 0.49
HDAC4 P56524 1/20 0.49
HDAC1 Q13547 1/20 0.49
HDAC7 Q8WUI4 1/20 0.49
HDAC2 Q92769 1/20 0.49
HDAC10 Q969S8 1/20 0.49
HDAC11 Q96DB2 1/20 0.49
HDAC9 Q9UKV0 1/20 0.49
HDAC5 Q9UQL6 1/20 0.49
TRPA1 O75762 1/20 0.49
RELA Q04206 1/20 0.49
CYP1A2 P05177 3/20 0.47
CYP1A1 P04798 3/20 0.47
CYP1B1 Q16678 3/20 0.47
ESR1 P03372 2/20 0.47
PTGS2 P35354 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17199711 0.95 ALDH1A1 (0.68) ALDH1A1CYP2A6HDAC8HDAC6HDAC3
SCHEMBL21738402 0.95 ALDH1A1 (0.68) ALDH1A1CYP2A6TRPA1RELACYP1A2
SCHEMBL10028279 0.95 ALDH1A1 (0.68) ALDH1A1CYP2A6TRPA1RELACYP1A2
SCHEMBL23908231 0.95 ALDH1A1 (0.68) ALDH1A1CYP2A6TRPA1RELACYP1A2
SCHEMBL23918295 0.95 ALDH1A1 (0.68) ALDH1A1CYP2A6TRPA1RELACYP1A2
SCHEMBL23908223 0.92 RELA (0.57) ALDH1A1HDAC8HDAC6HDAC3HDAC4
SCHEMBL23908220 0.92 RELA (0.57) ALDH1A1HDAC8HDAC6HDAC3HDAC4
SCHEMBL23908224 0.92 RELA (0.57) ALDH1A1HDAC8HDAC6HDAC3HDAC4
SCHEMBL7750911 0.90 ALDH1A1 (0.76) ALDH1A1CYP2A6TRPA1RELAKDM4E
SCHEMBL1128183 0.90 ALDH1A1 (0.76) ALDH1A1CYP2A6TRPA1RELAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210319957-A1 NOVEL COMPOUND, AND COMPOSITION FOR FORMING HOLE TRANSPORTING LAYER FOR PEROVSKITE SOLAR CELLS Tokyo Chemical Industry Co., Ltd. (JP) 2021-10-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210319957-A1 NOVEL COMPOUND, AND COMPOSITION FOR FORMING HOLE TRANSPORTING LAYER FOR PEROVSKITE SOLAR CELLS SLC43A1, SLC26A3, KCNT1 ALDH1A1 1257/4885CYP2A6 2621/4885HDAC8 4478/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.