SCHEMBL13385299

SCHEMBL13385299

COc1ccc(N(c2ccc(C=O)cc2)c2cccc(OC)c2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.58
CYP2A6 P11509 2/20 0.58
RELA Q04206 1/20 0.49
ALOX15 P16050 1/20 0.48
NPC1 O15118 1/20 0.47
RAB9A P51151 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
HSD17B1 P14061 2/20 0.45
HSD17B2 P37059 2/20 0.45
MTNR1A P48039 4/20 0.44
MTNR1B P49286 4/20 0.44
PTGER4 P35408 1/20 0.43
ALDH3A1 P30838 1/20 0.42
ALDH1A3 P47895 1/20 0.42
ESR1 P03372 1/20 0.42
CYP2A13 Q16696 1/20 0.41
TRPM8 Q7Z2W7 1/20 0.40
MAOB P27338 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
ENPP2 Q13822 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21738397 0.97 ALDH1A1 (0.52) ALDH1A1CYP2A6RELAALOX15NPC1
SCHEMBL5347489 0.87 ALDH1A1 (0.66) ALDH1A1CYP2A6RELATDP1ALDH3A1
SCHEMBL19275033 0.87 ALDH1A1 (0.66) ALDH1A1CYP2A6RELATDP1ALDH3A1
SCHEMBL1128183 0.87 ALDH1A1 (0.76) ALDH1A1CYP2A6RELAPTGER4ALDH3A1
SCHEMBL7750911 0.87 ALDH1A1 (0.76) ALDH1A1CYP2A6RELAPTGER4ALDH3A1
SCHEMBL8944101 0.87 HSD17B2 (0.50) ALDH1A1RELAALOX15HSD17B1HSD17B2
SCHEMBL18522462 0.87 ALOX15 (0.47) ALDH1A1RELAALOX15NPC1RAB9A
SCHEMBL13404828 0.86 ALOX15 (0.45) ALDH1A1CYP2A6ALOX15NPC1RAB9A
SCHEMBL13385296 0.85 RELA (0.49) RELAALOX15HSD17B1HSD17B2MTNR1A
SCHEMBL21738398 0.84 RELA (0.59) RELAESR1TTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7700248-B2 Organic charge transporting polymers including charge transport moieties and silane groups, and silsesquioxane compositions prepared therefrom EASTMAN KODAK COMPANY (US) 2010-04-20 US disclosed