Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
| ▸ | LCK | P06239 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26239498 | 0.80 | LCK (0.33) | LCKKDRTMPRSS2MAPK1 | |
| SCHEMBL26235345 | 0.79 | LCK (0.35) | MAOBGRM5LCKKDRTMPRSS2 | |
| SCHEMBL26823411 | 0.77 | TMPRSS2 (0.35) | LCKKDRTMPRSS2 | |
| SCHEMBL26832567 | 0.77 | TMPRSS2 (0.37) | LCKKDRTMPRSS2MAPK1 | |
| SCHEMBL25776452 | 0.76 | POLRMT (0.38) | — | |
| SCHEMBL26823086 | 0.75 | TMPRSS2 (0.40) | MAOBLCKKDRTMPRSS2MAPK1 | |
| SCHEMBL26831296 | 0.72 | — | — | |
| SCHEMBL26206065 | 0.71 | KDR (0.44) | MAOBLCKKDRMAPK1 | |
| SCHEMBL26209321 | 0.70 | KDM4E (0.38) | MAOBGRM5LCKKDRMAPK1 | |
| SCHEMBL26235125 | 0.70 | SMN1; SMN2 (0.38) | MAOBLCKKDRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023168254-A1 | ANTIVIRAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | GILEAD SCIENCES, INC. (US) | 2023-09-07 | — | — | WO | disclosed |