Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL26615665 | 0.99 | IDO1 (0.36) | IDO1TDO2CYP1A2CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL29986029 | 0.99 | IDO1 (0.36) | IDO1TDO2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL30910250 | 0.82 | ALDH1A1 (0.32) | CYP3A4P2RX7ALDH1A1 | |
| SCHEMBL29845425 | 0.77 | IDO1 (0.51) | IDO1TDO2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4550765 | 0.77 | IDO1 (0.51) | IDO1TDO2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL29656429 | 0.77 | IDO1 (0.51) | IDO1TDO2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4234796 | 0.77 | IDO1 (0.51) | IDO1TDO2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL14120782 | 0.77 | IDO1 (0.51) | IDO1TDO2CYP1A2CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL25358651 | 0.76 | IDO1 (0.54) | IDO1TDO2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL21132425 | 0.76 | CYP1A2 (0.40) | IDO1TDO2CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230348424-A1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | SCHRÖDINGER, INC. | 2023-11-02 | — | — | US | disclosed |
| WO-2023150291-A2 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | SCHRÖDINGER, INC. (US) | 2023-08-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230348424-A1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | APC, RCC2, CDC37 | IDO1 4361/4885TDO2 3719/4885CYP1A2 388/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.