Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC34A1 | Q06495 | 7/20 | 0.36 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 3/20 | 0.35 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | CCR8 | P51685 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26242512 | 0.73 | ADORA2A (0.44) | CACNA2D1CSNK1DMAPK14 | |
| SCHEMBL811754 | 0.71 | GRM5 (0.47) | GRM5MAPK14CCR1CCR5CCR8 | |
| SCHEMBL26242534 | 0.70 | KDM4E (0.50) | CCR1CCR5CCR8 | |
| SCHEMBL20075491 | 0.70 | SLC34A1 (0.47) | SLC34A1GRM5CSNK1DMAPK14TGFBR1 | |
| SCHEMBL21711425 | 0.68 | CSNK1D (0.36) | SLC34A1GRM5CSNK1DMAPK14GABRA5 | |
| SCHEMBL25551871 | 0.68 | CSNK1D (0.40) | SLC34A1GRM5CSNK1DMAPK14GABRA5 | |
| SCHEMBL30036913 | 0.68 | CSNK1D (0.40) | SLC34A1GRM5CSNK1DMAPK14GABRA5 | |
| SCHEMBL13830491 | 0.68 | NPC1 (0.41) | GRM5MAPK14CCR1CCR5CCR8 | |
| SCHEMBL25323378 | 0.67 | SLC34A1 (0.42) | SLC34A1GRM5CSNK1DMAPK14TGFBR1 | |
| SCHEMBL12668067 | 0.66 | KDM4E (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023150201-A2 | SODIUM CHANNEL BLOCKING COMPOUNDS, DERIVATIVES THEREOF, AND METHODS OF THEIR USE | LATIGO BIOTHERAPEUTICS, INC. (US) | 2023-08-10 | — | — | WO | disclosed |