SCHEMBL26246271

SCHEMBL26246271

COC(=O)[C@H]1CCCN1c1ccc(O)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
SCN9A Q15858 2/20 0.40
OPRM1 P35372 1/20 0.40
OPRD1 P41143 1/20 0.40
OPRK1 P41145 1/20 0.40
OGFRL1 Q5TC84 1/20 0.40
ADORA2A P29274 1/20 0.40
ADORA1 P30542 1/20 0.40
CNR2 P34972 2/20 0.40
FPR2 P25090 1/20 0.40
CYP2C8 P10632 1/20 0.40
CYP2C9 P11712 1/20 0.40
CNR1 P21554 1/20 0.40
CYP2C19 P33261 1/20 0.40
POLB P06746 1/20 0.40
LTA4H P09960 2/20 0.39
ALOX5 P09917 1/20 0.39
GAA P10253 1/20 0.39
CA2 P00918 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30940176 1.00 FFAR1 (0.41) FFAR1TDP1SCN9AOPRM1OPRD1
SCHEMBL3884242 0.87 SCN9A (0.41) FFAR1SCN9AOPRM1OPRD1OPRK1
SCHEMBL26246255 0.87 CNR2 (0.52) FFAR1CNR2FPR2CYP2C8CYP2C9
SCHEMBL26246472 0.87 SLC6A4 (0.45) FFAR1SCN9AOPRM1OPRD1OPRK1
SCHEMBL29035348 0.86 SCN9A (0.48) FFAR1SCN9AOPRM1OPRD1OPRK1
SCHEMBL26246339 0.86 SCN9A (0.48) FFAR1SCN9AOPRM1OPRD1OPRK1
Hydrochloric Acid SCHEMBL2333520 0.85 SCN9A (0.41) FFAR1SCN9AOPRM1OPRD1OPRK1
Hydrochloric Acid SCHEMBL29289926 0.85 SCN9A (0.47) FFAR1SCN9AOPRM1OPRD1OPRK1
SCHEMBL29349017 0.84 ALDH1A1 (0.46) FFAR1CNR2CNR1CASP3
SCHEMBL29349018 0.82 ALDH1A1 (0.44) OPRM1OPRD1OPRK1OGFRL1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230286973-A1 PROTEIN SECRETION INHIBITORS ENODIA THERAPEUTICS SAS (FR) 2023-09-14 US disclosed
US-20230286973-A1 PROTEIN SECRETION INHIBITORS ENODIA THERAPEUTICS SAS (FR) 2023-09-14 US disclosed
US-20230286973-A1 PROTEIN SECRETION INHIBITORS ENODIA THERAPEUTICS SAS (FR) 2023-09-14 US disclosed
EP-4204417-A1 PROTEIN SECRETION INHIBITORS Kezar Life Sciences (US) 2023-07-05 EP disclosed
CN-116194455-A Protein secretion inhibitor 科智生命科学公司 2023-05-30 CN disclosed
WO-2022047347-A1 PROTEIN SECRETION INHIBITORS KEZAR LIFE SCIENCES (US) 2022-03-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230286973-A1 PROTEIN SECRETION INHIBITORS SEC61B, SEC61A1, SEC61G FFAR1 3979/4885TDP1 2953/4885SCN9A 1746/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.