Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26249190 | 0.91 | MPO (0.31) | MPO | |
| SCHEMBL22525683 | 0.90 | IDO1 (0.33) | — | |
| SCHEMBL26253853 | 0.87 | PLA2G2C (0.34) | MPO | |
| SCHEMBL26254335 | 0.84 | MPO (0.38) | MPO | |
| SCHEMBL26249486 | 0.83 | MPO (0.32) | MPO | |
| SCHEMBL26253112 | 0.82 | MTNR1A (0.35) | MPO | |
| SCHEMBL26249507 | 0.80 | MPO (0.35) | MPO | |
| SCHEMBL26206155 | 0.80 | PPARG (0.34) | MPO | |
| SCHEMBL22525598 | 0.80 | AAK1 (0.42) | — | |
| SCHEMBL22527108 | 0.79 | ADRB2 (0.36) | MPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11746120-B2 | Stat degraders and uses thereof | KYMERA THERAPEUTICS, INC. (US) | 2023-09-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11746120-B2 | Stat degraders and uses thereof | STAT4, STAT1, STAT3 | MPO 2309/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.