Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.49 |
| ▸ | SLC18A3 | Q16572 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL410116 | 1.00 | OPRM1 (0.51) | OPRM1OPRK1OPRD1SLC18A3KDM4E | |
| SCHEMBL6726656 | 1.00 | OPRM1 (0.51) | OPRM1OPRK1OPRD1SLC18A3KDM4E | |
| SCHEMBL411151 | 1.00 | OPRM1 (0.51) | OPRM1OPRK1OPRD1SLC18A3KDM4E | |
| SCHEMBL410110 | 1.00 | OPRM1 (0.51) | OPRM1OPRK1OPRD1SLC18A3KDM4E | |
| SCHEMBL409665 | 1.00 | OPRM1 (0.51) | OPRM1OPRK1OPRD1SLC18A3KDM4E | |
| SCHEMBL31560969 | 0.90 | OPRM1 (0.43) | OPRM1OPRK1OPRD1SLC18A3GBA1 | |
| SCHEMBL18629949 | 0.83 | PSEN1 (0.47) | SLC18A3ALDH1A1 | |
| SCHEMBL17666343 | 0.83 | PSEN1 (0.47) | SLC18A3ALDH1A1 | |
| SCHEMBL20582658 | 0.83 | PSEN1 (0.47) | SLC18A3ALDH1A1 | |
| SCHEMBL6722047 | 0.83 | PSEN1 (0.47) | SLC18A3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163938-B2 | Aminocyclohexyl ether compounds and uses thereof | CARDIOME PHARMA CORP. (CA) | 2012-04-24 | — | — | US | disclosed |
| US-20110004006-A1 | AMINOCYCLOHEXYL ETHER COMPOUNDS AND USES THEREOF | CARDIOME PHARMA CORP. (CA) | 2011-01-06 | — | — | US | disclosed |
| US-20070254945-A1 | AMINOCYCLOHEXYL ETHER COMPOUNDS AND USES THEREOF | CARDIOME PHARMA CORP. (CA) | 2007-11-01 | — | — | US | disclosed |
| US-20070099983-A1 | Aminocyclohexyl ether compounds and uses thereof | CARDIOME PHARMA CORP. (CA) | 2007-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110004006-A1 | AMINOCYCLOHEXYL ETHER COMPOUNDS AND USES THEREOF | KCNH2, KCNC1, KCNH3 | OPRM1 2058/4885OPRK1 1082/4885OPRD1 1751/4885 |
| US-20070254945-A1 | AMINOCYCLOHEXYL ETHER COMPOUNDS AND USES THEREOF | KCNH2, KCNC1, KCNH3 | OPRM1 2058/4885OPRK1 1082/4885OPRD1 1751/4885 |
| US-20070099983-A1 | Aminocyclohexyl ether compounds and uses thereof | KCNH2, KCNC1, KCNH3 | OPRM1 2058/4885OPRK1 1082/4885OPRD1 1751/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.