Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26251306 | 0.83 | EPHX2 (0.46) | ALDH1A1SMN1; SMN2HTR2A | |
| SCHEMBL26251110 | 0.82 | SSTR4 (0.42) | ALDH1A1GAASMN1; SMN2HRH3POLB | |
| SCHEMBL26250934 | 0.82 | POLB (0.59) | ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL26251134 | 0.82 | SSTR4 (0.42) | ALDH1A1GAASMN1; SMN2HRH3POLB | |
| SCHEMBL6287003 | 0.81 | SSTR4 (0.41) | HRH3POLB | |
| SCHEMBL31152659 | 0.76 | POLB (0.65) | ALDH1A1GAASMN1; SMN2MAPTKDM4E | |
| SCHEMBL23976028 | 0.75 | RAB9A (0.53) | GAANPC1RAB9A | |
| SCHEMBL23694353 | 0.74 | GAA (0.48) | ALDH1A1GAASMN1; SMN2MAPTKDM4E | |
| SCHEMBL4961084 | 0.74 | HTR3A (0.56) | ALDH1A1MAPT | |
| SCHEMBL26250933 | 0.72 | ALDH1A1 (0.43) | ALDH1A1GAAHRH3SIGMAR1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023150186-A1 | DGK TARGETING COMPOUNDS AND USES THEREOF | ARVINAS OPERATIONS, INC. (US) | 2023-08-10 | — | — | WO | disclosed |