Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CXCL10 | P02778 | 1/20 | 0.34 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.34 |
| ▸ | CCL2 | P13500 | 1/20 | 0.34 |
| ▸ | CCL5 | P13501 | 1/20 | 0.34 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.32 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.32 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ASGR1 | P07306 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27020203 | 0.86 | MAPK1 (0.42) | MAPK1CXCL10CXCL8CCL2CCL5 | |
| SCHEMBL25746360 | 0.83 | CYP3A4 (0.43) | MAPK1CXCL10CXCL8CCL2CCL5 | |
| SCHEMBL29330037 | 0.83 | CYP3A4 (0.43) | MAPK1CXCL10CXCL8CCL2CCL5 | |
| SCHEMBL12192303 | 0.79 | MAPK1 (0.50) | MAPK1CXCL10CXCL8CCL2CCL5 | |
| SCHEMBL26257060 | 0.77 | CYP3A4 (0.42) | MAPK1CXCL10CXCL8CCL2CCL5 | |
| SCHEMBL10261606 | 0.77 | CYP3A4 (0.42) | MAPK1CXCL10CXCL8CCL2CCL5 | |
| SCHEMBL19390477 | 0.77 | CYP3A4 (0.42) | MAPK1CXCL10CXCL8CCL2CCL5 | |
| SCHEMBL19390475 | 0.77 | CYP3A4 (0.42) | MAPK1CXCL10CXCL8CCL2CCL5 | |
| SCHEMBL14316901 | 0.77 | CYP3A4 (0.51) | KMT2ACYP3A4MAPTCYP2C9CYP2C19 | |
| SCHEMBL23133631 | 0.76 | MAPK1 (0.65) | MAPK1MEN1KMT2ALGALS8LGALS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230295630-A1 | GALNAC COMPOSITIONS FOR IMPROVING SIRNA BIOAVAILABILITY | EMPIRICO INC. | 2023-09-21 | — | — | US | disclosed |