SCHEMBL26260211

SCHEMBL26260211

c1c[nH]c(-c2ccc3ccc(-c4ccc[nH]4)cc3c2)c1

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ABL1 P00519 1/20 0.44
CYP11B1 P15538 1/20 0.44
CYP11B2 P19099 1/20 0.44
HDAC1 Q13547 1/20 0.43
HDAC6 Q9UBN7 1/20 0.43
CHEK1 O14757 4/20 0.38
CNR1 P21554 1/20 0.37
PTPN1 P18031 2/20 0.37
ESR1 P03372 4/20 0.36
ESR2 Q92731 4/20 0.36
RIPK1 Q13546 1/20 0.36
NT5E P21589 1/20 0.36
NPC1 O15118 1/20 0.35
CDK2 P24941 1/20 0.35
GSK3A P49840 1/20 0.35
GSK3B P49841 1/20 0.35
GSTP1 P09211 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26265589 0.93 ABL1 (0.49) ABL1CYP11B1CYP11B2HDAC1HDAC6
SCHEMBL2457632 0.91 CYP11B1 (0.55) ABL1CYP11B1CYP11B2HDAC1HDAC6
SCHEMBL9419852 0.80 HDAC6 (0.57) HDAC1HDAC6CHEK1CNR1PTPN1
SCHEMBL2457170 0.79 AHR (0.52) ABL1CHEK1NPC1CDK2GSK3A
SCHEMBL2460316 0.79 NPC1 (0.61) CYP11B1CYP11B2NPC1
SCHEMBL20510943 0.78 CNR1 (0.47) ABL1HDAC1HDAC6CHEK1CNR1
SCHEMBL18821909 0.78 HDAC6 (0.45) HDAC1HDAC6CHEK1CNR1PTPN1
SCHEMBL2461379 0.77 DYRK1A (0.49) ABL1HDAC1HDAC6
SCHEMBL4562844 0.75 PGR (0.59)
SCHEMBL2458586 0.75 ABL1 (0.36) ABL1HDAC1HDAC6CHEK1CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230287262-A1 PHOTON UPCONVERSION COMPOSITION, FILM, METHOD FOR CONVERTING VISIBLE LIGHT INTO ULTRAVIOLET LIGHT, AND COMPOUND KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2023-09-14 US disclosed
US-20230287262-A1 PHOTON UPCONVERSION COMPOSITION, FILM, METHOD FOR CONVERTING VISIBLE LIGHT INTO ULTRAVIOLET LIGHT, AND COMPOUND KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2023-09-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230287262-A1 PHOTON UPCONVERSION COMPOSITION, FILM, METHOD FOR CONVERTING VISIBLE LIGHT INTO ULTRAVIOLET LIGHT, AND COMPOUND NUDC, CCNL2, SPIN3 ABL1 242/4885CYP11B1 3382/4885CYP11B2 3279/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.