SCHEMBL26263291

SCHEMBL26263291

CC[C@H](NC(=O)c1cccc(-c2ccc(OCC(F)(F)F)cc2)n1)C(=O)O

nearest known ligand 0.63

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SUCNR1 Q9BXA5 6/20 0.63
SCN9A Q15858 8/20 0.50
P2RY12 Q9H244 1/20 0.49
CNR2 P34972 3/20 0.47
CTSA P10619 1/20 0.47
CNR1 P21554 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26264467 0.90 SUCNR1 (0.78) SUCNR1SCN9AP2RY12CTSA
SCHEMBL26263580 0.88 SUCNR1 (0.60) SUCNR1SCN9AP2RY12CNR2CTSA
SCHEMBL26263285 0.88 SUCNR1 (0.81) SUCNR1SCN9ACNR2CTSACNR1
SCHEMBL26263294 0.86 SUCNR1 (0.60) SUCNR1SCN9AP2RY12CNR2CTSA
SCHEMBL26263279 0.85 SUCNR1 (0.61) SUCNR1SCN9AP2RY12CNR2CTSA
SCHEMBL26263268 0.82 SCN9A (0.60) SUCNR1SCN9ACNR2CTSACNR1
SCHEMBL26264469 0.78 SUCNR1 (0.71) SUCNR1SCN9AP2RY12CNR2CTSA
SCHEMBL26264461 0.77 SUCNR1 (1.00) SUCNR1SCN9ACTSA
SCHEMBL22939952 0.76 MAPT (0.47) SUCNR1SCN9A
SCHEMBL26264456 0.75 SUCNR1 (0.75) SUCNR1SCN9ACNR2CTSA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230293504-A1 TARGETING SUCNR1 TO REDUCE NEUROINFLAMMATION UNIV NEW YORK (US) 2023-09-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230293504-A1 TARGETING SUCNR1 TO REDUCE NEUROINFLAMMATION SUCNR1, SYNGR2, TSPO SUCNR1 1/4885SCN9A 1628/4885P2RY12 763/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.