Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | HINT1 | P49773 | 4/20 | 0.54 |
| ▸ | STING1 | Q86WV6 | 3/20 | 0.52 |
| ▸ | NT5E | P21589 | 1/20 | 0.52 |
| ▸ | PDE2A | O00408 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.50 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.50 |
| ▸ | GSK3A | P49840 | 2/20 | 0.49 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.49 |
| ▸ | PNP | P00491 | 2/20 | 0.49 |
| ▸ | TGM2 | P21980 | 1/20 | 0.48 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15070556 | 1.00 | HPGD (0.58) | HPGDHINT1STING1NT5EPDE2A | |
| SCHEMBL16375317 | 0.91 | HINT1 (0.55) | HPGDHINT1STING1NT5EGSK3A | |
| SCHEMBL26268365 | 0.91 | HINT1 (0.55) | HPGDHINT1STING1NT5EGSK3A | |
| SCHEMBL19035716 | 0.90 | HPGD (0.61) | HPGDHINT1STING1NT5EADORA3 | |
| SCHEMBL1738416 | 0.89 | HPGD (0.64) | HPGDHINT1STING1NT5EPDE3A | |
| SCHEMBL26208536 | 0.89 | HPGD (0.64) | HPGDHINT1STING1NT5EPDE3A | |
| SCHEMBL16317882 | 0.89 | HPGD (0.64) | HPGDHINT1STING1NT5EPDE3A | |
| SCHEMBL1738418 | 0.89 | HPGD (0.64) | HPGDHINT1STING1NT5EPDE3A | |
| SCHEMBL1738417 | 0.89 | HPGD (0.64) | HPGDHINT1STING1NT5EPDE3A | |
| SCHEMBL12031280 | 0.89 | HPGD (0.64) | HPGDHINT1STING1NT5EPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230374058-A1 | COMPOUNDS AND METHODS FOR TREATING DISEASE | ROME THERAPEUTICS, INC. | 2023-11-23 | — | — | US | disclosed |
| US-20230295212-A1 | COMPOUNDS AND METHODS FOR TREATING DISEASE | ROME THERAPEUTICS INC (US) | 2023-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230295212-A1 | COMPOUNDS AND METHODS FOR TREATING DISEASE | EHMT1, POLRMT, RNASE1 | HPGD 3566/4885HINT1 358/4885STING1 923/4885 |
| US-20230374058-A1 | COMPOUNDS AND METHODS FOR TREATING DISEASE | EHMT1, POLRMT, RNASE1 | HPGD 3566/4885HINT1 358/4885STING1 923/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.