Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 3/20 | 0.50 |
| ▸ | PPARG | P37231 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | FABP2 | P12104 | 1/20 | 0.50 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14030864 | 0.96 | ELANE (0.48) | ELANEPPARAPPARGHPGDFABP2 | |
| SCHEMBL13252904 | 0.95 | HPGD (0.47) | ELANEPPARAPPARGHPGDFABP2 | |
| SCHEMBL2628122 | 0.95 | HPGD (0.60) | ELANEPPARAPPARGHPGDFABP2 | |
| SCHEMBL13309960 | 0.95 | ELANE (0.47) | ELANEPPARAPPARGHPGDFABP2 | |
| SCHEMBL822836 | 0.91 | ELANE (0.59) | ELANEPPARAPPARGHPGDFABP2 | |
| SCHEMBL13250806 | 0.91 | ELANE (0.59) | ELANEPPARAPPARGHPGDFABP2 | |
| SCHEMBL15760406 | 0.87 | MMP13 (0.49) | ELANEESR1ESR2LMNACYP2C9 | |
| SCHEMBL16355302 | 0.87 | ALDH1A1 (0.48) | HPGDESR1ESR2LMNAMEN1 | |
| SCHEMBL15760405 | 0.87 | MMP13 (0.49) | ELANEESR1ESR2LMNACYP2C9 | |
| SCHEMBL14354267 | 0.86 | MAPT (0.49) | ELANEHPGDESR1ESR2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8431676-B2 | Aromatic compound and sulfonated polyarylene polymer | JSR CORPORATION (JP) | 2013-04-30 | — | — | US | disclosed |
| US-8163406-B2 | Membrane-electrode assembly for solid polymer electrolyte fuel cell | HONDA MOTOR CO., LTD. (JP) | 2012-04-24 | — | — | US | disclosed |
| US-20100174042-A1 | AROMATIC COMPOUND AND SULFONATED POLYARYLENE POLYMER | JSR CORPORATION (JP) | 2010-07-08 | — | — | US | disclosed |
| US-20080160381-A1 | MEMBRANE-ELECTRODE ASSEMBLY FOR SOLID POLYMER ELECTROLYTE FUEL CELL | HONDA MOTOR CO., LTD. (JP) | 2008-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100174042-A1 | AROMATIC COMPOUND AND SULFONATED POLYARYLENE POLYMER | SCO2, CBR1, CNOT1 | ELANE 2892/4885PPARA 1699/4885PPARG 2007/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.