Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 5/20 | 0.45 |
| ▸ | CTSS | P25774 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.42 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL754158 | 1.00 | MME (0.45) | MMECTSSCTSKOPRM1OPRK1 | |
| SCHEMBL753184 | 0.81 | CTRB1 (0.52) | MMEMMEL1 | |
| SCHEMBL753199 | 0.81 | CTRB1 (0.52) | MMEMMEL1 | |
| SCHEMBL7440669 | 0.81 | CTRB1 (0.52) | MMEMMEL1 | |
| SCHEMBL22092489 | 0.80 | MME (0.43) | MMECTSSCTSKOPRM1OPRK1 | |
| SCHEMBL17931625 | 0.78 | MME (0.49) | MMEMMEL1MEN1KMT2A | |
| SCHEMBL4665417 | 0.77 | CASP3 (0.51) | KMT2A | |
| SCHEMBL2317792 | 0.76 | MME (0.47) | MMEOPRM1OPRK1OPRD1MMEL1 | |
| SCHEMBL2317781 | 0.76 | MME (0.47) | MMEOPRM1OPRK1OPRD1MMEL1 | |
| SCHEMBL13702575 | 0.76 | MME (0.44) | MMEOPRM1OPRK1OPRD1MMEL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601188-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2017-10-18 | — | — | EP | disclosed |
| EP-2513091-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2017-04-12 | — | — | EP | disclosed |
| EP-2499132-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2017-02-15 | — | — | EP | disclosed |
| EP-2245027-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2012-04-25 | — | — | EP | disclosed |