Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 13/20 | 0.44 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | CTSD | P07339 | 5/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17424544 | 0.84 | BACE1 (0.46) | BACE1BACE2CTSDFOLH1 | |
| SCHEMBL16661562 | 0.83 | ADAMTS5 (0.43) | BACE1CTSD | |
| SCHEMBL17424527 | 0.82 | BACE1 (0.41) | BACE1BACE2CTSD | |
| SCHEMBL16199301 | 0.82 | BACE1 (0.41) | BACE1BACE2CTSD | |
| SCHEMBL10422239 | 0.82 | BACE1 (0.39) | BACE1CTSDFOLH1 | |
| SCHEMBL10422242 | 0.82 | BACE1 (0.39) | BACE1CTSDFOLH1 | |
| SCHEMBL16199302 | 0.81 | BACE1 (0.42) | BACE1CTSDFOLH1 | |
| SCHEMBL31631404 | 0.81 | MME (0.36) | — | |
| SCHEMBL17732669 | 0.81 | BACE1 (0.40) | BACE1BACE2CTSD | |
| SCHEMBL29695567 | 0.81 | GNPAT (0.47) | BACE1CTSDFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9334304-B2 | Self-assembling peptides bearing organic electronic functionality and applications employing the same | THE JOHNS HOPKINS UNIVERSITY (US) | 2016-05-10 | — | — | US | disclosed |
| US-20120101022-A1 | SELF-ASSEMBLING PEPTIDES BEARING ORGANIC ELECTRONIC FUNCTIONALITY AND APPLICATIONS EMPLOYING THE SAME | THE JOHNS HOPKINS UNIVERSITY (US) | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120101022-A1 | SELF-ASSEMBLING PEPTIDES BEARING ORGANIC ELECTRONIC FUNCTIONALITY AND APPLICATIONS EMPLOYING THE SAME | APP, IAPP, DNPEP | BACE1 12/4885BACE2 203/4885KEAP1 986/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.