Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 3/20 | 0.57 |
| ▸ | CYCS | P99999 | 4/20 | 0.56 |
| ▸ | STAT3 | P40763 | 1/20 | 0.54 |
| ▸ | STAT1 | P42224 | 1/20 | 0.54 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.37 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.37 |
| ▸ | MAPK6 | Q16659 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22332272 | 0.90 | TOP1 (0.70) | TOP1CYCSSTAT3STAT1ABCG2 | |
| SCHEMBL13411108 | 0.89 | ABCG2 (0.49) | TOP1CYCSSTAT3STAT1ABCG2 | |
| SCHEMBL11339474 | 0.88 | TOP1 (0.75) | TOP1CYCSSTAT3STAT1ABCG2 | |
| SCHEMBL140681 | 0.88 | TOP1 (0.67) | TOP1CYCSSTAT3STAT1ABCG2 | |
| SCHEMBL14706938 | 0.87 | ABCG2 (0.53) | TOP1CYCSSTAT3STAT1ABCG2 | |
| SCHEMBL2787415 | 0.87 | STAT3 (0.51) | TOP1CYCSSTAT3STAT1ABCG2 | |
| SCHEMBL11334086 | 0.87 | TOP1 (0.65) | TOP1CYCSSTAT3STAT1ABCG2 | |
| SCHEMBL28919688 | 0.87 | TOP1 (0.65) | TOP1CYCSSTAT3STAT1ABCG2 | |
| SCHEMBL14706940 | 0.86 | ABCG2 (0.51) | TOP1CYCSSTAT3STAT1ABCG2 | |
| SCHEMBL93007 | 0.85 | STAT3 (0.56) | TOP1CYCSSTAT3STAT1ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022216927-A9 | PORPHYRIN-HYDROPORPHYRIN COMPOUNDS, COMPOSITIONS COMPRISING THE SAME AND METHODS OF USE THEREOF | NORTH CAROLINA STATE UNIVERSITY (US) | 2023-09-14 | — | — | WO | disclosed |