Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 3/20 | 0.70 |
| ▸ | CYCS | P99999 | 4/20 | 0.68 |
| ▸ | STAT3 | P40763 | 1/20 | 0.65 |
| ▸ | STAT1 | P42224 | 1/20 | 0.65 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.40 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.40 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11339474 | 0.97 | TOP1 (0.75) | TOP1CYCSSTAT3STAT1ENPP2 | |
| SCHEMBL140681 | 0.97 | TOP1 (0.67) | TOP1CYCSSTAT3STAT1ENPP2 | |
| SCHEMBL11334086 | 0.96 | TOP1 (0.65) | TOP1CYCSSTAT3STAT1ENPP2 | |
| SCHEMBL28919688 | 0.96 | TOP1 (0.65) | TOP1CYCSSTAT3STAT1ENPP2 | |
| SCHEMBL17894094 | 0.92 | TOP1 (0.75) | TOP1CYCSSTAT3STAT1ENPP2 | |
| SCHEMBL28071729 | 0.91 | TOP1 (0.63) | TOP1CYCSSTAT3STAT1ENPP2 | |
| SCHEMBL26285347 | 0.90 | TOP1 (0.57) | TOP1CYCSSTAT3STAT1ENPP2 | |
| SCHEMBL14246834 | 0.90 | CYCS (0.62) | TOP1CYCSSTAT3STAT1ENPP2 | |
| SCHEMBL29664855 | 0.90 | CYCS (0.62) | TOP1CYCSSTAT3STAT1ENPP2 | |
| SCHEMBL22332236 | 0.87 | TOP1 (0.60) | TOP1CYCSSTAT3STAT1ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119371674-A | Preparation method of donor-acceptor type metal organic framework photocatalyst and application of photocatalytic amine oxide/thioether | 长沙理工大学 | 2025-01-28 | — | — | CN | claimed |
| EP-3206987-B2 | NANOPARTICLES FOR PHOTODYNAMIC THERAPY, X-RAY INDUCED PHOTODYNAMIC THERAPY, RADIOTHERAPY, CHEMOTHERAPY, IMMUNOTHERAPY, AND ANY COMBINATION THEREOF | UNIV CHICAGO (US) | 2024-07-24 | — | — | EP | claimed |
| CN-118268043-A | All-organic heterojunction photocatalyst and preparation method thereof | 淮北师范大学 | 2024-07-02 | — | — | CN | claimed |
| US-11826426-B2 | Nanoscale metal-organic layers and metal-organic nanoplates for x-ray induced photodynamic therapy, radiotherapy, radiodynamic therapy, chemotherapy, immunotherapy, and any combination thereof | THE UNIVERSITY OF CHICAGO (US) | 2023-11-28 | — | — | US | claimed |
| CN-115020670-A | MOFs modified silicon-based negative electrode material and preparation method thereof | 合肥国轩高科动力能源有限公司 | 2022-09-06 | — | — | CN | claimed |
| CN-105802612-A | Synthesis method of ratiometric fluorescent probe for detecting oxygen content in living cells | 济南大学 | 2016-07-27 | — | — | CN | claimed |
| WO-2025125384-A1 | HYDROGEL COMPOSITIONS | CAMBRIDGE ENTERPRISE LIMITED (GB) | 2025-06-19 | — | — | WO | disclosed |
| WO-2025125382-A1 | MOF NANOPARTICLES | CAMBRIDGE ENTERPRISE LIMITED (GB) | 2025-06-19 | — | — | WO | disclosed |
| CN-119371674-A | Preparation method of donor-acceptor type metal organic framework photocatalyst and application of photocatalytic amine oxide/thioether | 长沙理工大学 | 2025-01-28 | — | — | CN | disclosed |
| WO-2025010407-A2 | NANOSCALE METAL-ORGANIC FRAMEWORKS WITH X-RAY TRIGGERABLE PRODRUGS FOR COMBINATION RADIOTHERAPY, CHEMOTHERAPY, AND IMMUNOTHERAPY | THE UNIVERSITY OF CHICAGO (US) | 2025-01-09 | — | — | WO | disclosed |
| EP-3206987-B2 | NANOPARTICLES FOR PHOTODYNAMIC THERAPY, X-RAY INDUCED PHOTODYNAMIC THERAPY, RADIOTHERAPY, CHEMOTHERAPY, IMMUNOTHERAPY, AND ANY COMBINATION THEREOF | UNIV CHICAGO (US) | 2024-07-24 | — | — | EP | disclosed |
| CN-118268043-A | All-organic heterojunction photocatalyst and preparation method thereof | 淮北师范大学 | 2024-07-02 | — | — | CN | disclosed |
| CN-113831351-B | Novel tetrapyrrole derivatives and application thereof | 上海先辉医药科技有限公司 | 2024-05-03 | — | — | CN | disclosed |
| US-20230293698-A1 | METAL-ORGANIC FRAMEWORKS DELIVER SMALL MOLECULES AND BIOMACROMOLECULES FOR CANCER IMMUNOTHERAPY | UNIV CHICAGO (US) | 2023-09-21 | — | — | US | disclosed |
| EP-4138784-A1 | METAL-ORGANIC FRAMEWORKS DELIVER SMALL MOLECULES AND BIOMACROMOLECULES FOR CANCER IMMUNOTHERAPY | The University of Chicago (US) | 2023-03-01 | — | — | EP | disclosed |
| CN-115020670-A | MOFs modified silicon-based negative electrode material and preparation method thereof | 合肥国轩高科动力能源有限公司 | 2022-09-06 | — | — | CN | disclosed |
| CN-112870355-B | Composite nano-porous platinum-based coordination polymer and preparation method and application thereof | 中山大学 | 2022-04-01 | — | — | CN | disclosed |
| US-20200254095-A1 | NANOSCALE METAL-ORGANIC LAYERS AND METAL-ORGANIC NANOPLATES FOR X-RAY INDUCED PHOTODYNAMIC THERAPY, RADIOTHERAPY, RADIODYNAMIC THERAPY, CHEMOTHERAPY, IMMUNOTHERAPY, AND ANY COMBINATION THEREOF | THE UNIVERSITY OF CHICAGO | 2020-08-13 | — | — | US | disclosed |
| CN-105802612-A | Synthesis method of ratiometric fluorescent probe for detecting oxygen content in living cells | 济南大学 | 2016-07-27 | — | — | CN | disclosed |
| CN-105802612-A | Synthesis method of ratiometric fluorescent probe for detecting oxygen content in living cells | 济南大学 | 2016-07-27 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230293698-A1 | METAL-ORGANIC FRAMEWORKS DELIVER SMALL MOLECULES AND BIOMACROMOLECULES FOR CANCER IMMUNOTHERAPY | ORC3, RBM3, RNMT | TOP1 266/4885CYCS 2330/4885STAT3 1293/4885 |
| US-11826426-B2 | Nanoscale metal-organic layers and metal-organic nanoplates for x-ray induced photodynamic therapy, radiotherapy, radiodynamic therapy, chemotherapy, immunotherapy, and any combination thereof | CD274, PDCD1LG2, PDCD1 | TOP1 166/4885CYCS 2415/4885STAT3 2688/4885 |
| US-20200254095-A1 | NANOSCALE METAL-ORGANIC LAYERS AND METAL-ORGANIC NANOPLATES FOR X-RAY INDUCED PHOTODYNAMIC THERAPY, RADIOTHERAPY, RADIODYNAMIC THERAPY, CHEMOTHERAPY, IMMUNOTHERAPY, AND ANY COMBINATION THEREOF | CD274, PDCD1LG2, PDCD1 | TOP1 166/4885CYCS 2415/4885STAT3 2688/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.