SCHEMBL140681

SCHEMBL140681

O=C(O)c1ccc(-c2c3nc(cc4ccc(cc5nc(cc6ccc2[nH]6)C=C5)[nH]4)C=C3)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TOP1 P11387 3/20 0.67
▸ CYCS P99999 4/20 0.65
▸ STAT3 P40763 1/20 0.62
▸ STAT1 P42224 1/20 0.62
▸ ENPP2 Q13822 1/20 0.41
▸ ABCG2 Q9UNQ0 1/20 0.39
▸ MMP2 P08253 1/20 0.39
▸ MMP9 P14780 1/20 0.39
▸ MMP8 P22894 1/20 0.39
▸ MMP13 P45452 1/20 0.39
▸ GRIK1 P39086 1/20 0.39
▸ GRIK2 Q13002 1/20 0.39
▸ GRIK3 Q13003 1/20 0.39
▸ KDM4E B2RXH2 2/20 0.39
▸ ALDH1A1 P00352 2/20 0.39
▸ HPGD P15428 2/20 0.39
▸ KMT2A Q03164 2/20 0.39
▸ GPR35 Q9HC97 1/20 0.38
▸ GLA P06280 1/20 0.36
▸ GAA P10253 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11334086 0.99 TOP1 (0.65) TOP1CYCSSTAT3STAT1ENPP2
SCHEMBL28919688 0.99 TOP1 (0.65) TOP1CYCSSTAT3STAT1ENPP2
SCHEMBL22332272 0.97 TOP1 (0.70) TOP1CYCSSTAT3STAT1ENPP2
SCHEMBL11339474 0.95 TOP1 (0.75) TOP1CYCSSTAT3STAT1ENPP2
SCHEMBL17894094 0.95 TOP1 (0.75) TOP1CYCSSTAT3STAT1ENPP2
SCHEMBL28071729 0.89 TOP1 (0.63) TOP1CYCSSTAT3STAT1ENPP2
SCHEMBL11293560 0.88 STAT3 (0.56) TOP1CYCSSTAT3STAT1ENPP2
SCHEMBL26285347 0.88 TOP1 (0.57) TOP1CYCSSTAT3STAT1ENPP2
SCHEMBL29664855 0.87 CYCS (0.62) TOP1CYCSSTAT3STAT1ENPP2
SCHEMBL14246834 0.87 CYCS (0.62) TOP1CYCSSTAT3STAT1ENPP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1659 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122057527-A Hydrodewaxing polycyclic aromatic hydrocarbon catalyst, preparation method and application thereof 中国石油化工股份有限公司 2026-05-19 — — CN claimed
CN-122037220-A Porphyrin-Cu2+Complex nano-sheet and preparation method and application thereof 河南省科学院激光制造研究所 2026-05-15 — — CN claimed
CN-122005794-A MOF-based composite sensitizer and preparation method and application thereof 理工清科(重庆)先进材料研究院有限公司 2026-05-12 — — CN claimed
CN-122005903-A Temperature-sensitive hydrogel dressing and preparation method and application thereof 十堰市太和医院(湖北医药学院附属医院) 2026-05-12 — — CN claimed
CN-122016778-A Method for detecting ferrous ions of heavy metals in environment 南京师范大学 2026-05-12 — — CN claimed
US-12542215-B2 Detection of early-stage lung cancer in sputum using automated flow cytometry and machine learning BIOAFFINITY TECHNOLOGIES, INC. (US) 2026-02-03 — — US claimed
WO-2025125382-A1 MOF NANOPARTICLES CAMBRIDGE ENTERPRISE LIMITED (GB) 2025-06-19 — — WO claimed
WO-2025125384-A1 HYDROGEL COMPOSITIONS CAMBRIDGE ENTERPRISE LIMITED (GB) 2025-06-19 — — WO claimed
CN-120137190-A Carboxyl lithium porphyrin supermolecule fast-charging anode material of lithium ion battery, and preparation method and application thereof 山东大学 2025-06-13 — — CN claimed
CN-120131953-A Targeted nano-drug with sonodynamic activity, and preparation method and application thereof 中山大学·深圳 2025-06-13 — — CN claimed
US-20060002822-A1 Oxygen sensitive probe AGILENT TECHNOLOGIES, INC. 2006-01-05 — — US claimed
US-20050245673-A1 Care and/or make-up cosmetic composition structured with silicone polymers and organogelling agents, in rigid form L'OREAL S.A. (FR) 2005-11-03 — — US claimed
EP-1515684-A2 CARE AND/OR MAKE-UP COSMETIC COMPOSITION STRUCTURED WITH SILICONE POLYMERS AND ORGANOGELLING AGENTS, IN RIGID FORM L'OREAL (FR) 2005-03-23 — — EP claimed
US-20040116500-A1 Methods and compositions to treat lung diseases SAKALOSKY GEORGE P (US) 2004-06-17 — — US claimed
WO-2003105788-A2 CARE AND/OR MAKE-UP COSMETIC COMPOSITION STRUCTURED WITH SILICONE POLYMERS AND ORGANOGELLING AGENTS, IN RIGID FORM L'OREAL (FR) 2003-12-24 — — WO claimed
US-6660762-B2 Administering porphyrin compound; respiratory system disorders SAKALOSKY GEORGE P (US) 2003-12-09 — — US claimed
US-20030004204-A1 Methods and compositions to treat lung diseases SAKALOSKY GEORGE P (US) 2003-01-02 — — US claimed
EP-0811626-B1 Use of metallo-porphyrin conjugates for the detection of biological substances ROCHE DIAGNOSTICS GMBH (DE) 2002-08-14 — — EP claimed
US-6004530-A REACTING METALLO-PORPHYRIN HAVING ONE TO FOUR CARBOXYLIC ACID GROUPS WITH CARBODIIMIDE, 1-HYDROXYBENZOTRIAZOLE AND ACTIVE ESTER COUPLING AGENT TO FORM ACTIVE ESTER ROCHE DIAGNOSTICS GMBH (DE) 1999-12-21 — — US claimed
EP-0811626-A1 Use of metallo-porphyrin conjugates for the detection of biological substances Roche Diagnostics GmbH (DE) 1997-12-10 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030004204-A1 Methods and compositions to treat lung diseases PPOX, BPGM, CLN6 TOP1 596/4885CYCS 448/4885STAT3 4868/4885
US-12542215-B2 Detection of early-stage lung cancer in sputum using automated flow cytometry and machine learning CD14, CTSL, MKI67 TOP1 813/4885CYCS 352/4885STAT3 81/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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