Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 4/20 | 0.38 |
| ▸ | ACHE | P22303 | 3/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 6/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 6/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 5/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5773887 | 0.76 | KDM4E (0.39) | BCHEACHEOPRL1OGFRL1KDM4E | |
| SCHEMBL13036980 | 0.76 | KDM4E (0.39) | BCHEACHEOPRL1OGFRL1KDM4E | |
| SCHEMBL22455735 | 0.74 | OPRL1 (0.35) | BCHEACHECHRNB4CHRNA3CHRNB2 | |
| SCHEMBL26502000 | 0.74 | CHRNB2 (0.41) | MAOBCHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL26501366 | 0.74 | PDE4B (0.30) | CHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL2628597 | 0.72 | HSD17B10 (0.41) | — | |
| SCHEMBL2628596 | 0.72 | BIRC2 (0.36) | — | |
| SCHEMBL12039281 | 0.71 | CYP3A4 (0.41) | BCHEMAOBKDM4E | |
| SCHEMBL19798127 | 0.70 | HSD17B10 (0.41) | — | |
| SCHEMBL29108930 | 0.70 | ALDH1A1 (0.50) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8580297-B2 | Components for producing amphoteric liposomes | MARINA BIOTECH, INC. (US) | 2013-11-12 | — | — | US | disclosed |
| US-20120100205-A1 | COMPONENTS FOR PRODUCING AMPHOTERIC LIPOSOMES | MARINA BIOTECH, INC. | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120100205-A1 | COMPONENTS FOR PRODUCING AMPHOTERIC LIPOSOMES | PHOSPHO1, SGMS1, CHMP4B | BCHE 2197/4885ACHE 4484/4885MAOB 4176/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.