Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | NAMPT | P43490 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26286625 | 1.00 | KDM4E (0.41) | KDM4EALDH1A1LMNAL3MBTL1TSHR | |
| SCHEMBL22875137 | 0.92 | KDM4E (0.46) | KDM4EALDH1A1LMNAL3MBTL1TSHR | |
| SCHEMBL12424283 | 0.78 | ALDH1A1 (0.47) | KDM4EALDH1A1LMNAL3MBTL1TSHR | |
| SCHEMBL26287965 | 0.77 | TLR9 (0.38) | ALDH1A1NAMPT | |
| SCHEMBL15014609 | 0.77 | ALDH1A1 (0.56) | KDM4EALDH1A1LMNAL3MBTL1KMT2A | |
| SCHEMBL24456998 | 0.77 | DPP4 (0.41) | ALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL24456643 | 0.77 | DPP4 (0.41) | ALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL24456648 | 0.77 | DPP4 (0.41) | ALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL13308126 | 0.76 | ALDH1A1 (0.43) | KDM4EALDH1A1LMNAL3MBTL1TSHR | |
| SCHEMBL26286132 | 0.75 | RECQL (0.50) | KDM4EALDH1A1TSHRPKMHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023172737-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | KUMQUAT BIOSCIENCES INC. (US) | 2023-09-14 | — | — | WO | disclosed |