Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | KDM6B | O15054 | 6/20 | 0.49 |
| ▸ | KDM4A | O75164 | 6/20 | 0.49 |
| ▸ | KDM4D | Q6B0I6 | 6/20 | 0.49 |
| ▸ | HIF1AN | Q9NWT6 | 6/20 | 0.49 |
| ▸ | KDM2A | Q9Y2K7 | 6/20 | 0.49 |
| ▸ | KDM3B | Q7LBC6 | 5/20 | 0.49 |
| ▸ | KDM5B | Q9UGL1 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PLA2G7 | Q13093 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15925206 | 0.73 | KMT2A (0.50) | LMNAALDH1A1KDM6BKDM4AKDM4D | |
| SCHEMBL3545647 | 0.73 | PLA2G7 (0.67) | LMNAALDH1A1KDM6BKDM4AKDM4D | |
| SCHEMBL23542344 | 0.71 | ALDH1A1 (0.50) | LMNAALDH1A1ATMKDM4EUSP2 | |
| SCHEMBL25407708 | 0.70 | ALDH1A1 (0.66) | LMNAALDH1A1ATMKDM4EUSP2 | |
| SCHEMBL10980944 | 0.70 | KDM6B (0.47) | LMNAALDH1A1KDM6BKDM4AKDM4D | |
| SCHEMBL20511270 | 0.69 | ALDH1A1 (0.82) | LMNAALDH1A1KDM4ETSHRKMT2A | |
| SCHEMBL25408513 | 0.68 | PDE10A (0.35) | ALDH1A1KDM4ETSHR | |
| SCHEMBL11421113 | 0.68 | KDM6B (0.53) | LMNAKDM6BKDM4AKDM4DHIF1AN | |
| SCHEMBL10734964 | 0.68 | KDM6B (0.46) | LMNAALDH1A1ATMKDM6BKDM4A | |
| SCHEMBL22042833 | 0.67 | PDE9A (0.52) | ALDH1A1POLBTSHRKMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230279008-A1 | PTGR2 INHIBITORS AND THEIR USE | NATIONAL TAIWAN UNIVERSITY (TW) | 2023-09-07 | — | — | US | disclosed |
| US-20230279008-A1 | PTGR2 INHIBITORS AND THEIR USE | NATIONAL TAIWAN UNIVERSITY (TW) | 2023-09-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230279008-A1 | PTGR2 INHIBITORS AND THEIR USE | PTGFR, PTGIR, PTGDR2 | LMNA 3834/4885ALDH1A1 1177/4885ATM 3674/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.