SCHEMBL2629285

SCHEMBL2629285

Cc1cnc(N2CCCC2)cn1

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 2/20 0.45
GPR119 Q8TDV5 2/20 0.45
SMN1; SMN2 Q16637 3/20 0.44
CRHBP P24387 1/20 0.44
CRHR2 Q13324 1/20 0.44
CNR2 P34972 5/20 0.44
MAPT P10636 3/20 0.42
UBE2T Q9NPD8 1/20 0.42
ALDH1A1 P00352 1/20 0.41
LMNA P02545 1/20 0.41
ALOX12 P18054 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
HTT P42858 1/20 0.38
IP6K1 Q92551 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL240638 0.98 SMN1; SMN2 (0.47) KCNH2GPR119SMN1; SMN2CRHBPCRHR2
SCHEMBL82210 0.85 HRH4 (0.46) ALDH1A1
SCHEMBL8207362 0.83 KCNH2 (0.43) KCNH2GPR119SMN1; SMN2CRHBPCRHR2
SCHEMBL81828 0.83 HTR3A (0.52) KCNH2GPR119NPSR1RAB9AL3MBTL1
SCHEMBL2629281 0.81 PLD1 (0.47) KCNH2GPR119ALDH1A1
SCHEMBL807298 0.81 ALDH1A1 (0.54) SMN1; SMN2CRHBPCRHR2CNR2MAPT
SCHEMBL26340620 0.81 KCNH2 (0.42) KCNH2GPR119SMN1; SMN2CNR2MAPT
SCHEMBL24878940 0.81 PDE9A (0.40) KCNH2GPR119SMN1; SMN2ALDH1A1
SCHEMBL82204 0.80 HRH3 (0.41) KCNH2GPR119MAPTALDH1A1
SCHEMBL81679 0.80 GAA (0.47) KCNH2GPR119SMN1; SMN2MAPTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230125712-A1 SELF-LUMINOUS DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2023-04-27 US disclosed
US-20230125712-A1 SELF-LUMINOUS DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2023-04-27 US disclosed
US-20230026009-A1 WAVELENGTH SELECTIVE ABSORPTION FILTER, POLARIZING PLATE, ORGANIC ELECTROLUMINESCENT DISPLAY DEVICE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2023-01-26 US disclosed
US-20230012898-A1 LAMINATE, DISPLAY DEVICE, AND ORGANIC ELECTROLUMINESCENT DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2023-01-19 US disclosed
EP-4066834-A1 HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF PI3K-GAMMA MEDIATED DISORDERS Infinity Pharmaceuticals, Inc. (US) 2022-10-05 EP disclosed
EP-3613743-B1 PROCESSES FOR THE PREPARATION OF 1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINE DERIVATIVES INTELLIKINE LLC (US) 2022-03-16 EP disclosed
EP-3305778-B1 INHIBITORS OF PLASMA KALLIKREIN KALVISTA PHARMACEUTICALS LTD (GB) 2022-01-19 EP disclosed
EP-3441392-B1 A PHARMACEUTICAL COMPOSITION FOR ORAL ADMINISTRATION INTELLIKINE LLC (US) 2021-12-15 EP disclosed
US-20210277249-A1 RESIN COMPOSITION, OPTICAL FILTER, IMAGE DISPLAY DEVICE, SOLID-STATE IMAGING ELEMENT, AND COLORANT MIXTURE FUJIFILM CORPORATION (JP) 2021-09-09 US disclosed
EP-3811974-A1 TREATMENT OF CANCERS USING PI3 KINASE ISOFORM MODULATORS Infinity Pharmaceuticals, Inc. (US) 2021-04-28 EP disclosed
US-20100087646-A1 REAGENT FOR ORGANIC SYNTHESIS REACTION CONTAINING ORGANIC TRIOL BORATE SALT WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2010-04-08 US disclosed
US-7662823-B2 Pharmaceutical formulations of substituted azaindoleoxoacetic piperazine derivatives BRISTOL-MYERS SQUIBB COMPANY (US) 2010-02-16 US disclosed
US-20090312319-A1 CERTAIN CHEMICAL ENTITIES, COMPOSITIONS AND METHODS INTELLIKINE 2009-12-17 US disclosed
US-20090306095-A1 COMPOSITION AND ANTIVIRAL ACTIVITY OF SUBSTITUTED AZAINDOLEOXOACETIC PIPERAZINE DERIVATIVES BRISTOL-MYERS SQUIBB COMPANY 2009-12-10 US disclosed
US-20090221611-A1 Fused Triazole Tachykinin Receptor Antagonists MERCK SHARP & DOHME CORP. 2009-09-03 US disclosed
US-20090221611-A1 Fused Triazole Tachykinin Receptor Antagonists MERCK SHARP & DOHME CORP. 2009-09-03 US disclosed
US-7501420-B2 Composition and antiviral of substituted azaindoleoxoacetic piperazine derivatives BRISTOL-MYERS SQUIBB COMPANY (US) 2009-03-10 US disclosed
US-20080119480-A1 COMPOSITION AND ANTIVIRAL ACTIVITY OF SUBSTITUTED AZAINDOLEOXOACETIC PIPERAZINE DERIVATIVES BRISTOL-MYERS SQUIBB COMPANY 2008-05-22 US disclosed
US-7354924-B2 Composition and antiviral activity of substituted azaindoleoxoacetic piperazine derivatives BRISTOL-MYERS SQUIBB COMPANY (US) 2008-04-08 US disclosed
WO-2007081897-A2 FUSED TRIAZOLE TACHYKININ RECEPTOR ANTAGONISTS MERCK & CO., INC. (US) 2007-07-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090312319-A1 CERTAIN CHEMICAL ENTITIES, COMPOSITIONS AND METHODS PIK3CA, PIK3CG, PIK3CB KCNH2 3855/4885GPR119 444/4885SMN1; SMN2 3325/4885
US-20090306095-A1 COMPOSITION AND ANTIVIRAL ACTIVITY OF SUBSTITUTED AZAINDOLEOXOACETIC PIPERAZINE DERIVATIVES ITPA, IDO1, IDO2 KCNH2 3001/4885GPR119 1837/4885SMN1; SMN2 4726/4885
US-20080119480-A1 COMPOSITION AND ANTIVIRAL ACTIVITY OF SUBSTITUTED AZAINDOLEOXOACETIC PIPERAZINE DERIVATIVES ITPA, IDO1, IDO2 KCNH2 3001/4885GPR119 1837/4885SMN1; SMN2 4726/4885
US-20100087646-A1 REAGENT FOR ORGANIC SYNTHESIS REACTION CONTAINING ORGANIC TRIOL BORATE SALT ORC3, OXSR1, OSTC KCNH2 860/4885GPR119 3927/4885SMN1; SMN2 3837/4885
US-20230012898-A1 LAMINATE, DISPLAY DEVICE, AND ORGANIC ELECTROLUMINESCENT DISPLAY DEVICE EPCAM, ICAM1, STRA6 KCNH2 4085/4885GPR119 4088/4885SMN1; SMN2 2764/4885
US-20090221611-A1 Fused Triazole Tachykinin Receptor Antagonists TACR1, TACR2, NPSR1 KCNH2 198/4885GPR119 370/4885SMN1; SMN2 4291/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.