Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 3/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.32 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21149313 | 0.83 | HDAC2 (0.38) | CHRNB2CHRNA4CHRNB4CHRNA3TSHR | |
| SCHEMBL21025382 | 0.83 | CHRNB2 (0.52) | CHRNB2CHRNA4CHRNB4CHRNA3TSHR | |
| SCHEMBL12206738 | 0.83 | CHRNB2 (0.38) | CHRNB2CHRNA4CHRNB4CHRNA3TSHR | |
| SCHEMBL10139547 | 0.83 | CHRNB2 (0.50) | CHRNB2CHRNA4CHRNB4CHRNA3TSHR | |
| SCHEMBL30674446 | 0.81 | CHRNB2 (0.47) | CHRNB2CHRNA4CHRNB4CHRNA3TSHR | |
| SCHEMBL20343638 | 0.79 | HSD11B1 (0.42) | CHRNB2CHRNA4CHRNB4CHRNA3TSHR | |
| SCHEMBL19686575 | 0.79 | CHRNB2 (0.40) | CHRNB2CHRNA4CHRNB4CHRNA3TSHR | |
| SCHEMBL19686595 | 0.79 | CHRNB2 (0.37) | CHRNB2CHRNA4CHRNB4CHRNA3TSHR | |
| SCHEMBL14752960 | 0.79 | MAPT (0.39) | CHRNB2CHRNA4CHRNB4CHRNA3TSHR | |
| SCHEMBL2603257 | 0.79 | GPR119 (0.44) | PDE4BGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023172737-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | KUMQUAT BIOSCIENCES INC. (US) | 2023-09-14 | — | — | WO | disclosed |