SCHEMBL26298538

SCHEMBL26298538

Cc1c(-c2ccccc2)c2c3ccccc3n(C)c2n1N

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 2/20 0.43
▸ KMT2A Q03164 2/20 0.43
▸ SMN1; SMN2 Q16637 1/20 0.43
▸ KDM4E B2RXH2 4/20 0.41
▸ MAPT P10636 2/20 0.41
▸ CYP11B2 P19099 2/20 0.41
▸ GPR3 P46089 1/20 0.40
▸ HSD17B10 Q99714 4/20 0.39
▸ HPGD P15428 3/20 0.39
▸ NPSR1 Q6W5P4 2/20 0.39
▸ ALDH1A1 P00352 4/20 0.38
▸ CYP2C19 P33261 2/20 0.37
▸ TOP2A P11388 1/20 0.37
▸ TDP1 Q9NUW8 2/20 0.36
▸ GLA P06280 1/20 0.36
▸ GAA P10253 1/20 0.36
▸ HTT P42858 1/20 0.36
▸ MEN1 O00255 1/20 0.36
▸ ALKBH5 Q6P6C2 1/20 0.36
▸ FTO Q9C0B1 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26168131 0.86 LMNA (0.46) LMNAKMT2ASMN1; SMN2KDM4EMAPT
SCHEMBL26168233 0.81 KDM4E (0.46) KMT2AKDM4EMAPTCYP11B2GPR3
SCHEMBL26168251 0.77 LMNA (0.44) LMNAKMT2ASMN1; SMN2KDM4EMAPT
SCHEMBL26169830 0.77 KMT2A (0.42) LMNAKMT2ASMN1; SMN2KDM4EMAPT
SCHEMBL26168263 0.76 KDM4E (0.41) KMT2AKDM4EMAPTCYP11B2GPR3
SCHEMBL26168119 0.75 KMT2A (0.54) LMNAKMT2ASMN1; SMN2KDM4EMAPT
SCHEMBL29634190 0.75 KMT2A (0.54) LMNAKMT2ASMN1; SMN2KDM4EMAPT
SCHEMBL15024745 0.70 GPR3 (0.64) KMT2AKDM4EMAPTGPR3HSD17B10
SCHEMBL19233951 0.69 KDM4E (0.47) KMT2AKDM4EMAPTGPR3HSD17B10
SCHEMBL9955515 0.69 KDM4E (0.51) LMNAKMT2ASMN1; SMN2KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230276696-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2023-08-31 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230276696-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, PORCN LMNA 2148/4885KMT2A 4003/4885SMN1; SMN2 4189/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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