SCHEMBL26301484

SCHEMBL26301484

Cc1cc(C)c(C)c(-c2ccc3ccc(CC(C)C)cc3[n+]2C)c1

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.31
GABRB2 P47870 1/20 0.31
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26301483 0.91 NR3C1 (0.31) GABRA1GABRB2KDM4E
SCHEMBL26781739 0.86 GABRA1 (0.32) GABRA1GABRB2
SCHEMBL26793365 0.85 CYP1A2 (0.33)
SCHEMBL26834390 0.82 HTR2A (0.35) GABRA1GABRB2
SCHEMBL26796937 0.81 GABRA1 (0.32) GABRA1GABRB2
SCHEMBL26782101 0.81
SCHEMBL26049656 0.81 CYP1A2 (0.33) KDM4E
SCHEMBL26781570 0.80 LMNA (0.37)
SCHEMBL26836500 0.80 HTR2A (0.39) GABRA1GABRB2
SCHEMBL25518666 0.79 NR3C1 (0.33) GABRA1GABRB2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11832456-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-11-28 US disclosed
EP-3981776-B1 USE OF AN ANCILLARY LIGAND IN A PHOSPHORESCENT METAL COMPLEX COMPOUND UNIVERSAL DISPLAY CORP (US) 2023-11-15 EP disclosed
US-20230295204-A1 METAL COMPLEX AND USE THEREOF GUANGDONG AGLAIA OPTOELECTRONIC MATERIALS CO., LTD (CN) 2023-09-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11832456-B2 Organic electroluminescent materials and devices CPNE4, CYBA, EPCAM GABRA1 2194/4885GABRB2 3045/4885KDM4E 807/4885
US-20230295204-A1 METAL COMPLEX AND USE THEREOF IK, CYBA, LAS1L GABRA1 3669/4885GABRB2 4259/4885KDM4E 4522/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.