SCHEMBL26301683

SCHEMBL26301683

CC(=O)c1ccn2c(C(=O)c3ccccc3)cc(-c3ccncc3)c2c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FNTA P49354 4/20 0.46
▸ FNTB P49356 4/20 0.46
▸ BAZ2B Q9UIF8 9/20 0.44
▸ BAZ2A Q9UIF9 7/20 0.44
▸ BRD4 O60885 1/20 0.44
▸ BRD2 P25440 1/20 0.44
▸ BRD3 Q15059 1/20 0.44
▸ MAPT P10636 1/20 0.42
▸ ALDH1A1 P00352 1/20 0.42
▸ MEN1 O00255 1/20 0.42
▸ KMT2A Q03164 1/20 0.42
▸ BRD9 Q9H8M2 2/20 0.41
▸ MAPK14 Q16539 1/20 0.40
▸ HTT P42858 1/20 0.39
▸ TUBB4A P04350 1/20 0.39
▸ TUBB P07437 1/20 0.39
▸ TUBA3C P0DPH7 1/20 0.39
▸ TUBA1B P68363 1/20 0.39
▸ TUBA4A P68366 1/20 0.39
▸ TUBB4B P68371 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26301036 0.91 FNTA (0.51) FNTAFNTBBAZ2BBAZ2ABRD4
SCHEMBL26301013 0.89 FNTA (0.49) FNTAFNTBBAZ2BBAZ2ABRD4
SCHEMBL26301735 0.85 BAZ2B (0.46) FNTAFNTBBAZ2BBAZ2AALDH1A1
SCHEMBL26300978 0.85 BACE1 (0.47) FNTAFNTBBAZ2BBAZ2AALDH1A1
SCHEMBL26301819 0.84 FNTA (0.61) FNTAFNTBBAZ2BBAZ2ABRD4
SCHEMBL26301057 0.83 BAZ2B (0.47) FNTAFNTBBAZ2BBAZ2AMAPT
SCHEMBL26304108 0.83 BAZ2B (0.62) FNTAFNTBBAZ2BBAZ2AMAPT
SCHEMBL26300911 0.82 BACE1 (0.47) FNTAFNTBBAZ2BBAZ2AMAPT
SCHEMBL26301159 0.81 ALDH1A1 (0.48) FNTAFNTBBAZ2BBAZ2AMAPT
SCHEMBL26301762 0.81 BAZ2B (0.47) FNTAFNTBBAZ2BBAZ2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4233864-A1 INTERFERON GENE STIMULATOR COMPOSITION COMPRISING INDOLIZINE DERIVATIVE AS ACTIVE INGREDIENT Ajou University Industry-Academic Cooperation Foundation (KR) 2023-08-30 — — EP disclosed
Send feedback