SCHEMBL26301718

SCHEMBL26301718

CC(=O)c1ccn2c(C(=O)c3ccccc3)cc(-c3ccc(C)c(N)c3)c2c1

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ FNTA P49354 6/20 0.46
▸ FNTB P49356 6/20 0.46
▸ BAZ2B Q9UIF8 7/20 0.45
▸ BAZ2A Q9UIF9 7/20 0.45
▸ ALDH1A1 P00352 1/20 0.39
▸ HDAC2 Q92769 2/20 0.37
▸ AKT1 P31749 1/20 0.36
▸ AKT2 P31751 1/20 0.36
▸ HPGD P15428 1/20 0.35
▸ HTT P42858 1/20 0.35
▸ SMN1; SMN2 Q16637 1/20 0.35
▸ NPSR1 Q6W5P4 1/20 0.35
▸ L3MBTL1 Q9Y468 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26301829 0.87 FNTA (0.54) FNTAFNTBBAZ2BBAZ2AHTT
SCHEMBL26301735 0.86 BAZ2B (0.46) FNTAFNTBBAZ2BBAZ2AALDH1A1
SCHEMBL26301013 0.85 FNTA (0.49) FNTAFNTBBAZ2BBAZ2AALDH1A1
SCHEMBL26301036 0.84 FNTA (0.51) FNTAFNTBBAZ2BBAZ2AALDH1A1
SCHEMBL26301057 0.80 BAZ2B (0.47) FNTAFNTBBAZ2BBAZ2AALDH1A1
SCHEMBL26304108 0.80 BAZ2B (0.62) FNTAFNTBBAZ2BBAZ2AALDH1A1
SCHEMBL26301683 0.79 FNTA (0.46) FNTAFNTBBAZ2BBAZ2AALDH1A1
SCHEMBL26300978 0.79 BACE1 (0.47) FNTAFNTBBAZ2BBAZ2AALDH1A1
SCHEMBL26301762 0.77 BAZ2B (0.47) FNTAFNTBBAZ2BBAZ2AALDH1A1
SCHEMBL25401220 0.74 FNTA (0.51) FNTAFNTBBAZ2BBAZ2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4233864-A1 INTERFERON GENE STIMULATOR COMPOSITION COMPRISING INDOLIZINE DERIVATIVE AS ACTIVE INGREDIENT Ajou University Industry-Academic Cooperation Foundation (KR) 2023-08-30 — — EP disclosed
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