Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | PKM | P14618 | 1/20 | 0.65 |
| ▸ | ACHE | P22303 | 2/20 | 0.63 |
| ▸ | TACR2 | P21452 | 3/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
| ▸ | EGFR | P00533 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31305358 | 0.82 | ALDH1A1 (0.76) | MAPTLMNAPKMACHEALDH1A1 | |
| SCHEMBL30673257 | 0.80 | ALDH1A1 (0.82) | LMNAMAPK1ALDH1A1POLBEPHX2 | |
| SCHEMBL28928585 | 0.79 | MAPK1 (0.70) | MAPTLMNAACHEMAPK1ALDH1A1 | |
| SCHEMBL7367181 | 0.78 | HTT (0.70) | MAPK1EGFRALDH1A1HTTKMT2A | |
| SCHEMBL26393865 | 0.77 | MAPK1 (0.67) | MAPK1ALDH1A1POLBKMT2A | |
| SCHEMBL28724172 | 0.77 | TSHR (0.68) | MAPTALDH1A1HTTKMT2A | |
| Hydrochloric Acid SCHEMBL7371797 | 0.77 | HTT (0.68) | LMNAMAPK1EGFRALDH1A1HTT | |
| SCHEMBL28673108 | 0.76 | HSD17B10 (0.52) | MAPTLMNAPKMMAPK1ALDH1A1 | |
| SCHEMBL1463825 | 0.76 | POLB (0.61) | LMNAMAPK1ALDH1A1POLBHTT | |
| SCHEMBL1956688 | 0.76 | LTA4H (0.79) | EGFRHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141467-A2 | COMPOSITIONS, METHODS, AND DEVELOPMENT OF ARID4B INHIBITORS | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2023-07-27 | — | — | WO | disclosed |