Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | HBB | P68871 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28665126 | 0.92 | ALDH1A1 (0.51) | HSD17B10ALDH1A1LMNAKDM4EHPGD | |
| SCHEMBL28667737 | 0.92 | KMT2A (0.53) | HSD17B10ALDH1A1LMNAKDM4EHPGD | |
| SCHEMBL28670860 | 0.86 | KDM4E (0.51) | HSD17B10ALDH1A1LMNAKDM4EHPGD | |
| SCHEMBL28680120 | 0.84 | HSD17B10 (0.49) | HSD17B10ALDH1A1LMNAKDM4EHPGD | |
| SCHEMBL28693130 | 0.83 | SMN1; SMN2 (0.52) | HSD17B10ALDH1A1KDM4EHPGDPOLB | |
| SCHEMBL28682360 | 0.80 | ADORA2B (0.49) | HSD17B10ALDH1A1KDM4EKMT2APOLB | |
| SCHEMBL28667089 | 0.79 | ALDH1A1 (0.56) | HSD17B10ALDH1A1LMNAKDM4EHPGD | |
| SCHEMBL28683947 | 0.78 | HTT (0.57) | ALDH1A1LMNAKDM4EKMT2APOLB | |
| SCHEMBL28289454 | 0.78 | ALDH1A1 (0.54) | HSD17B10ALDH1A1LMNAKDM4EHPGD | |
| SCHEMBL28675935 | 0.76 | KMT2A (0.54) | HSD17B10ALDH1A1LMNAKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109824574-B | Indole-3-carboxamides and their use | 沈阳药科大学 | 2021-12-28 | — | — | CN | disclosed |