Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.83 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.60 |
| ▸ | PDE4A | P27815 | 1/20 | 0.58 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.58 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8761800 | 0.91 | PKM (1.00) | PKMPDE4DPDE4APDE4BPDE4C | |
| SCHEMBL26308271 | 0.91 | PKM (0.70) | PKMPDE4DPDE4APDE4BPDE4C | |
| SCHEMBL2887392 | 0.77 | PDE4D (0.66) | PKMPDE4DPDE4APDE4BPDE4C | |
| SCHEMBL2887769 | 0.77 | PDE4D (0.63) | PKMPDE4DPDE4APDE4BPDE4C | |
| SCHEMBL17664663 | 0.77 | MEN1 (0.72) | PKMKMT2AMEN1ALDH1A1POLB | |
| SCHEMBL12682342 | 0.77 | MAPT (0.71) | PKMKMT2AMEN1ALDH1A1POLB | |
| SCHEMBL11244161 | 0.76 | PDE4D (0.81) | PKMPDE4DKMT2AMEN1ALDH1A1 | |
| SCHEMBL14363233 | 0.76 | TP53 (0.68) | PKMPDE4DKMT2AMEN1ALDH1A1 | |
| SCHEMBL6993698 | 0.76 | CA12 (0.65) | PKMKMT2AMEN1ALDH1A1POLB | |
| SCHEMBL2969970 | 0.75 | KDM4E (0.67) | PKMPDE4DKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141467-A2 | COMPOSITIONS, METHODS, AND DEVELOPMENT OF ARID4B INHIBITORS | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2023-07-27 | — | — | WO | disclosed |