Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.52 |
| ▸ | PIM1 | P11309 | 1/20 | 0.52 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.52 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.52 |
| ▸ | PDE4A | P27815 | 1/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.51 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26307991 | 0.91 | PKM (0.83) | PKMALDH1A1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL8761800 | 0.83 | PKM (1.00) | PKMALDH1A1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL14424707 | 0.76 | MAPT (0.58) | ALDH1A1HPGDCYP1A2CYP2C19KDM4E | |
| SCHEMBL13400966 | 0.75 | MAPT (0.62) | ALDH1A1HPGDCYP1A2CYP2C19KMT2A | |
| SCHEMBL11244161 | 0.75 | PDE4D (0.81) | PKMALDH1A1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL2818082 | 0.75 | MAPT (0.53) | PKMALDH1A1HPGDCYP1A2CYP3A4 | |
| SCHEMBL14363233 | 0.74 | TP53 (0.68) | PKMALDH1A1HPGDCYP1A2CYP3A4 | |
| SCHEMBL2979309 | 0.74 | CA12 (0.64) | PKMALDH1A1HPGDCYP1A2CYP3A4 | |
| SCHEMBL2969970 | 0.74 | KDM4E (0.67) | PKMALDH1A1HPGDCYP1A2CYP3A4 | |
| SCHEMBL13783367 | 0.73 | ALDH1A1 (0.68) | ALDH1A1HPGDCYP1A2CYP2C19KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141467-A2 | COMPOSITIONS, METHODS, AND DEVELOPMENT OF ARID4B INHIBITORS | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2023-07-27 | — | — | WO | disclosed |