SCHEMBL2631150

SCHEMBL2631150

CC(=O)/C(N)=C(/C)C(N)=O

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.44
BLM P54132 2/20 0.44
ALOX15 P16050 1/20 0.44
PMP22 Q01453 1/20 0.44
TDP1 Q9NUW8 2/20 0.42
TSHR P16473 1/20 0.38
THPO P40225 1/20 0.38
LDHA P00338 2/20 0.33
LDHB P07195 1/20 0.33
CRBN Q96SW2 1/20 0.32
CA4 P22748 2/20 0.32
ALDH1A1 P00352 1/20 0.31
OR51E2 Q9H255 1/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4779556 0.78 LMNA (0.58) LMNABLMALOX15PMP22TDP1
SCHEMBL27696587 0.78 LMNA (0.58) LMNABLMALOX15PMP22TDP1
SCHEMBL4141273 0.78 LMNA (0.58) LMNABLMALOX15PMP22TDP1
SCHEMBL2631747 0.76 LMNA (0.47) LMNABLMALOX15PMP22TDP1
SCHEMBL27476647 0.74 LMNA (0.54) LMNABLMALOX15PMP22TDP1
SCHEMBL598557 0.73
SCHEMBL9485089 0.73 LMNA (0.44) LMNABLMALOX15PMP22TDP1
SCHEMBL11464126 0.72
SCHEMBL17241077 0.72
SCHEMBL15605 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1249731-B1 Photosensitive composition and negative working lithographic printing plate FUJIFILM CORP (JP) 2012-04-25 EP disclosed