Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.55 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.54 |
| ▸ | METTL14 | Q9HCE5 | 1/20 | 0.54 |
| ▸ | XBP1 | P17861 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KDM1A | O60341 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.42 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26312242 | 0.81 | BCHE (0.59) | IDO1ALDH1A1LMNAMAPTSMN1; SMN2 | |
| Coptisine SCHEMBL156866 | 0.71 | IDO1 (1.00) | IDO1METTL3METTL14ALDH1A1LMNA | |
| Coptisine SCHEMBL31392604 | 0.71 | IDO1 (1.00) | IDO1METTL3METTL14ALDH1A1LMNA | |
| Coptisine SCHEMBL29931632 | 0.71 | IDO1 (1.00) | IDO1METTL3METTL14ALDH1A1LMNA | |
| Coptisine SCHEMBL2441815 | 0.70 | IDO1 (0.98) | IDO1METTL3METTL14ALDH1A1LMNA | |
| Coptisine SCHEMBL154528 | 0.70 | METTL3 (1.00) | IDO1METTL3METTL14ALDH1A1LMNA | |
| SCHEMBL15624081 | 0.69 | BCHE (0.52) | IDO1ALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL298574 | 0.69 | BCHE (0.62) | IDO1ALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL14513580 | 0.67 | BCHE (0.63) | IDO1ALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL14513581 | 0.67 | BCHE (0.63) | IDO1ALDH1A1LMNAMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11725006-B2 | Hydrophilic berberine-type derivative and application thereof in preparing drug | INSTITUTE OF MATERIA MEDIC, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2023-08-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11725006-B2 | Hydrophilic berberine-type derivative and application thereof in preparing drug | SLC7A1, ABCB11, ABCC1 | IDO1 2696/4885METTL3 3178/4885METTL14 2974/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.