SCHEMBL26313007

SCHEMBL26313007

CNc1nc(C(=O)O)c(NC)nc1C(=O)O

nearest known ligand 0.36

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
MAPT P10636 1/20 0.36
HCAR2 Q8TDS4 2/20 0.35
NPSR1 Q6W5P4 1/20 0.35
PIM1 P11309 3/20 0.34
KDM4E B2RXH2 2/20 0.33
HCAR3 P49019 1/20 0.33
KDM4C Q9H3R0 1/20 0.32
YTHDC1 Q96MU7 1/20 0.32
TDP1 Q9NUW8 1/20 0.31
PIN1 Q13526 2/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
PTPN1 P18031 1/20 0.30
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9453105 0.78 KDM4C (0.32) ALDH1A1SMN1; SMN2MAPTPIM1KDM4C
SCHEMBL19482662 0.77 HPGD (0.37) ALDH1A1SMN1; SMN2HCAR2KDM4E
SCHEMBL3579095 0.75 GRM5 (0.38) ALDH1A1SMN1; SMN2MAPTHCAR2KDM4E
SCHEMBL9319179 0.74 PGK1 (0.58) ALDH1A1KDM4E
SCHEMBL3577400 0.74 GRM5 (0.56) ALDH1A1SMN1; SMN2PIM1HCAR3YTHDC1
SCHEMBL13346059 0.74 GRM5 (0.37) ALDH1A1SMN1; SMN2MAPTHCAR2PIM1
SCHEMBL14399014 0.72 KDM4E (0.36) ALDH1A1KDM4ETDP1
SCHEMBL3580632 0.72 KDM4E (0.43) ALDH1A1MAPTHCAR2NPSR1KDM4E
SCHEMBL30206064 0.72 KDM4E (0.43) ALDH1A1MAPTHCAR2NPSR1KDM4E
SCHEMBL30588867 0.71 KEAP1 (0.32) ALDH1A1KDM4EYTHDC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11708336-B2 Anodic oxidation of 5-aminouracil MEDIBEACON INC. (US) 2023-07-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11708336-B2 Anodic oxidation of 5-aminouracil DPYD, DHODH, AASDHPPT ALDH1A1 297/4885SMN1; SMN2 2424/4885MAPT 4050/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.