Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SDHB | P21912 | 15/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 2/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26313164 | 0.92 | SDHB (0.49) | SDHBMAPTTP53PDE4APDE4B | |
| SCHEMBL26313170 | 0.88 | MKNK1 (0.46) | SDHBMAPTTP53MEN1KMT2A | |
| SCHEMBL19805843 | 0.86 | SDHB (0.55) | SDHBMAPTTP53PDE4APDE4B | |
| SCHEMBL26313167 | 0.84 | SDHB (0.44) | SDHBMAPTTP53MEN1KMT2A | |
| SCHEMBL19805988 | 0.84 | SDHB (0.53) | SDHBMAPTTP53 | |
| SCHEMBL29976656 | 0.82 | SDHB (0.58) | SDHB | |
| SCHEMBL20985680 | 0.82 | SDHB (0.58) | SDHB | |
| SCHEMBL20985678 | 0.82 | SDHB (0.48) | SDHBMAPTTP53MEN1KMT2A | |
| SCHEMBL29976030 | 0.82 | SDHB (0.48) | SDHBMAPTTP53MEN1KMT2A | |
| SCHEMBL19806088 | 0.82 | SDHB (0.54) | SDHBMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11725000-B2 | Apoptosis inhibitors | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2023-08-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11725000-B2 | Apoptosis inhibitors | BAX, SDHA, SDHB | SDHB 3/4885MAPT 2304/4885TP53 160/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.