Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 14/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 12/20 | 0.47 |
| ▸ | HPGD | P15428 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 11/20 | 0.40 |
| ▸ | NOS2 | P35228 | 10/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26313495 | 0.88 | SLC6A2 (0.55) | SLC6A2SLC6A4HPGDALDH1A1CYP2D6 | |
| SCHEMBL26316127 | 0.87 | SLC6A2 (0.58) | SLC6A2SLC6A4HPGDALDH1A1CYP2D6 | |
| SCHEMBL25413031 | 0.87 | SLC6A2 (0.43) | SLC6A2SLC6A4HPGDALDH1A1CYP2D6 | |
| SCHEMBL25413033 | 0.87 | SLC6A2 (0.43) | SLC6A2SLC6A4HPGDALDH1A1CYP2D6 | |
| SCHEMBL30597276 | 0.87 | SLC6A2 (0.43) | SLC6A2SLC6A4HPGDALDH1A1CYP2D6 | |
| SCHEMBL26313491 | 0.87 | SLC6A2 (0.65) | SLC6A2SLC6A4HPGDALDH1A1CYP2D6 | |
| SCHEMBL25412471 | 0.86 | SLC6A4 (0.62) | SLC6A2SLC6A4CYP2D6NOS2KCNH2 | |
| SCHEMBL25412474 | 0.86 | SLC6A4 (0.62) | SLC6A2SLC6A4CYP2D6NOS2KCNH2 | |
| SCHEMBL26316185 | 0.81 | SLC6A2 (0.53) | SLC6A2SLC6A4HPGDALDH1A1CYP2D6 | |
| SCHEMBL26313486 | 0.81 | NOS2 (0.46) | SLC6A2SLC6A4CYP2D6NOS2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230286913-A1 | INHIBITORS OF NITRIC OXIDE SYNTHASES (NOS), PHARMACEUTICAL PRODUCTS THEREOF, AND METHODS THEREOF | Gacter Inc. (US) | 2023-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230286913-A1 | INHIBITORS OF NITRIC OXIDE SYNTHASES (NOS), PHARMACEUTICAL PRODUCTS THEREOF, AND METHODS THEREOF | NOS1, NOS3, NOS2 | SLC6A2 1484/4885SLC6A4 841/4885HPGD 99/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.